สืบค้นงานวิจัย
Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions : A randomized controlled trial
Ratree Maenthaisong - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions : A randomized controlled trial
ผู้แต่ง / หัวหน้าโครงการ (EN): Ratree Maenthaisong
บทคัดย่อ (EN): Introduction: Trikatu is composed of dried fruits of Piper nigrum L and Piper retrofractum Vahl, and dried rhizomes of Zingiber officinale R. Although this preparation has been used to relieve pruritis, pain, and inflammation for a long time, there is no clinical evidence to confirm its efficacy and safety. Therefore, we performed a double-blind, within person-randomized controlled study of 30 healthy volunteers to determine efficacy and safety of topical Trikatu on mosquito bite reactions. Methods: All subjects were bitten by Aedes aegypti laboratory mosquitoes on their forearms and they were randomly assigned arms to apply either Trikatu or reference product on the mosquito bite papule. The main outcome was the difference of papule size reduction at 30 min, measured by a caliper, between the Trikatu and reference arms. Pruritis, redness, pain, and patient satisfaction were assessed at 15, 30, 60, 180, and 360 min as secondary outcomes.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=446
เผยแพร่โดย (EN): a Clinical Pharmacy Research Unit, Department of Clinical Pharmacy, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand b Discipline of Pharmacy, Monash University Sunway Campus, Jalan Lagoon Selatan, Bandar Sunway 46150, Selangor, Malaysia c Center of Pharmaceutical Outcomes Research, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand d School of Pharmacy, University of Wisconsin, Madison, WI, USA e School of Population Health, University of Queensland, Brisbane, QLD, Australia f Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand g The National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand h Clinical Research Center, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand
คำสำคัญ (EN): A randomized controlled trial
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions : A randomized controlled trial
Ratree Maenthaisong
a Clinical Pharmacy Research Unit, Department of Clinical Pharmacy, Faculty of Pharmacy, Mahasarakham University, Mahasarakham, Thailand b Discipline of Pharmacy, Monash University Sunway Campus, Jalan Lagoon Selatan, Bandar Sunway 46150, Selangor, Malaysia c Center of Pharmaceutical Outcomes Research, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand d School of Pharmacy, University of Wisconsin, Madison, WI, USA e School of Population Health, University of Queensland, Brisbane, QLD, Australia f Department of Pharmaceutical Technology, Faculty of Pharmaceutical Sciences, Naresuan University, Phitsanulok, Thailand g The National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand h Clinical Research Center, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand
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