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Microgeographically diverse Plasmodium vivax populations at the Thai-Myanmar border
Gupta B. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Microgeographically diverse Plasmodium vivax populations at the Thai-Myanmar border
ผู้แต่ง / หัวหน้าโครงการ (EN): Gupta B.
บทคัดย่อ (EN): Malaria transmission along international borders of the Greater Mekong Subregion is a big challenge for regional malaria elimination. At the Thai-Myanmar border, Plasmodium falciparum cases have dropped dramatically; however, increasing P. vivax prevalence and the emerging reports on hidden malaria burden due to asymptomatic infections demand attention. We conducted cross-sectional surveys to detect asymptomatic malaria infections in a small village located at Thai-Myanmar border and genotyped P. vivax infections in order to understand the level of genetic diversity on such a microgeographic scale. PCR/RFLP and DNA sequencing identified high levels of genetic polymorphisms at both Pvmsp3α and Pvmsp3β loci among P. vivax infections. Combining the PCR/RFLP patterns of Pvmsp3α and Pvmsp3β, a total of 10 genotypes were observed among 17 samples, while concatenated DNA sequences of Pvmsp3α and 3β generated 14 haplotypes with haplotype diversity of 0.97. These markedly diverse parasites on a microgeographic scale suggest the circulation of a considerably large parasite population at the international border. © 2016 Elsevier B.V.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84988985916&doi=10.1016%2fj.meegid.2016.09.021&partnerID=40&md5=efc2eef775cd819151deb58a226ecd56
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Young Adult
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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Microgeographically diverse Plasmodium vivax populations at the Thai-Myanmar border
Gupta B.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
Genetic diversity of the Plasmodium vivax multidrug resistance 1 gene in Thai parasite populations Molecular evolution of PvMSP3a block II in Plasmodium vivax from diverse geographic origins Use of insecticide-treated nets among pig owners living in Japanese encephalitis endemic areas of northern Myanmar Genetic diversity of Plasmodium falciparum histidine-rich protein 2 in the China-Myanmar border area Estimating gestational age in late presenters to antenatal care in a resource-limited setting on the Thai-Myanmar border Validation of the refugee health screener-15 for the assessment of perinatal depression among karen and Burmese women on the Thai-myanmar border Empirical lessons regarding contraception in a protracted refugee setting: A descriptive study from Maela camp on the Thai-Myanmar border 1996 - 2015 Differential roles of an Anopheline midgut GPI-anchored protein in mediating Plasmodium falciparum and Plasmodium vivax ookinete invasion Immunogenicity and antigenicity of Plasmodium vivax merozoite surface protein 10 Co-occurrence of swine cysticercosis due to Taenia solium and Taenia hydatigena in ethnic minority villages at the Thai-Myanmar border
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