คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Piyada Wangroongsarb

เผยแพร่โดย

1 Department of Medical Sciences, National Institute of Health, Nonthaburi, Thailand, 2 Department of Veterinary Science, Osaka Prefecture University, Osaka, Japan, 3 Department of Microbiology, Osaka City Institute of Public Health and Environmental Sciences, Osaka, Japan, 4 Department of Medical Sciences, Nonthaburi, Thailand, 5 Department of Virology, Osaka University, Osaka, Japan

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หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand Group B Streptococcal bacteremia burden and trends over time, 2007-15, Thailand Wolbachia supergroups A and B in natural populations of medically important filth flies (Diptera : Muscidae, Calliphoridae, and Sarcophagidae) in Thailand Draft Genome Sequence of a Clostridium botulinum Isolate from Thailand Harboring the Subtype bont/B8 Gene Molecular detection and characterization of noroviruses in river water in Thailand Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Molecular Epidemiology of Carbapenem-Resistant Enterobacterales in Thailand, 20162018. Prevalence of toxigenic Clostridium perfringens strains isolated from dried spur pepper in Thailand Emergence and Characterization of Unusual DS-1-Like G1P[8] Rotavirus Strains in Children with Diarrhea in Thailand

คัดลอก URL

ชื่อเรื่อง (EN):	Molecular Characterization of Clostridium botulinum Isolates from Foodborne Outbreaks in Thailand, 2010
ผู้แต่ง / หัวหน้าโครงการ (EN):	Piyada Wangroongsarb
บทคัดย่อ (EN):	Background: Thailand has had several foodborne outbreaks of botulism, one of the biggest being in 2006 when laboratory investigations identified the etiologic agent as Clostridium botulinum type A. Identification of the etiologic agent from outbreak samples is laborious using conventional microbiological methods and the neurotoxin mouse bioassay. Advances in molecular techniques have added enormous information regarding the etiology of outbreaks and characterization of isolates. We applied these methods in three outbreaks of botulism in Thailand in 2010. Methodology/Principal Findings: A total of 19 cases were involved (seven each in Lampang and Saraburi and five in Maehongson provinces). The first outbreak in Lampang province in April 2010 was associated with C. botulinum type F, which was detected by conventional methods. Outbreaks in Saraburi and Maehongson provinces occurred in May and December were due to C. botulinum type A1(B) and B that were identified by conventional methods and molecular techniques, respectively. The result of phylogenetic sequence analysis showed that C. botulinum type A1(B) strain Saraburi 2010 was close to strain Iwate 2007. Molecular analysis of the third outbreak in Maehongson province showed C. botulinum type B8, which was different from B1–B7 subtype. The nontoxic component genes of strain Maehongson 2010 revealed that ha33, ha17 and botR genes were close to strain Okra (B1) while ha70 and ntnh genes were close to strain 111 (B2). Conclusion/Significance: This study demonstrates the utility of molecular genotyping of C. botulinum and how it contributes to our understanding the epidemiology and variation of boNT gene. Thus, the recent botulism outbreaks in Thailand were induced by various C. botulinum types.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=441
เผยแพร่โดย (EN):	1 Department of Medical Sciences, National Institute of Health, Nonthaburi, Thailand, 2 Department of Veterinary Science, Osaka Prefecture University, Osaka, Japan, 3 Department of Microbiology, Osaka City Institute of Public Health and Environmental Sciences, Osaka, Japan, 4 Department of Medical Sciences, Nonthaburi, Thailand, 5 Department of Virology, Osaka University, Osaka, Japan
คำสำคัญ (EN):	Foodborne Outbreaks in Thailand
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science