คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Maljkovic Berry

เผยแพร่โดย

1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA 2 Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Paris, France. 3 CNRS, URA3012, Paris 75015, France 4 Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France 5 Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, 20910, USA. 6 Department of Medicine, Upstate Medical University of New York, Syracuse, New York, NY, 13210, USA 7 Queen Sirikit National Institute of Child Health, Bangkok, Thailand 8 National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand 9 Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand 10 Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand 11 International Vaccine Institute, Seoul, South Korea 12 Department of Biology, University of Florida, Gainesville, FL 32610, USA 13 Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA

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งานวิจัยที่แนะนำ Monitoring of resistance in laboratory susceptible strain and field population strains of Culex quinquefasciatus to Bacillus thuringiensis var. israelensis (Bti), Bacillus sphaericus (Bsph) and temeph DIVERSITY OF THE CASSIICOLIN GENE IN CORYNESPORA CASSIICOLA OF RUBBER TREE IN CHINA Effect of Three Rootstocks on the Same Scion PR107 of Hevea brasiliensis Spatial patterns of local species richness reveal importance of frugivores for tropical forest diversity Spatial variations in dengue transmission in schools in Thailand Population structure shapes copy number variation in malaria parasites Genetic Analysis and Population Structure of Rubber Tree for Association Mapping Population genetic structure of Zeugodacus tau species complex in Thailand Diversity of microorganism with effect Biodeterioration of Historical Ruins in Phanakornsiayutthaya Provinceอ NATURALLY OCCURRING NANOMATRIX STRUCTURE FORMED IN NATURAL RUBBER AND ITS EFFECT ONVISCOELASTIC PROPERTIES

คัดลอก URL

ชื่อเรื่อง (EN):	Dengue diversity across spatial and temporal scales: Local structure and the effect of host population size
ผู้แต่ง / หัวหน้าโครงการ (EN):	Maljkovic Berry
บทคัดย่อ (EN):	A fundamental mystery for dengue and other infectious pathogens is how observed patterns of cases relate to actual chains of individual transmission events. These pathways are intimately tied to the mechanisms by which strains interact and compete across spatial scales. Phylogeographic methods have been used to characterize pathogen dispersal at global and regional scales but have yielded few insights into the local spatiotemporal structure of endemic transmission. Using geolocated genotype (800 cases) and serotype (17,291 cases) data, we show that in Bangkok, Thailand, 60% of dengue cases living <200 meters apart come from the same transmission chain, as opposed to 3% of cases separated by 1 to 5 kilometers. At distances <200 meters from a case (encompassing an average of 1300 people in Bangkok), the effective number of chains is 1.7. This number rises by a factor of 7 for each 10-fold increase in the population of the "enclosed" region. This trend is observed regardless of whether population density or area increases, though increases in density over 7000 people per square kilometer do not lead to additional chains. Within Thailand these chains quickly mix, and by the next dengue season viral lineages are no longer highly spatially structured within the country. In contrast, viral flow to neighboring countries is limited. These findings are consistent with local, density-dependent transmission and implicate densely populated communities as key sources of viral diversity, with home location the focal point of transmission. These findings have important implications for targeted vector control and active surveillance.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=514
เผยแพร่โดย (EN):	1 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA 2 Mathematical Modelling of Infectious Diseases Unit, Institut Pasteur, Paris, France. 3 CNRS, URA3012, Paris 75015, France 4 Center of Bioinformatics, Biostatistics and Integrative Biology, Institut Pasteur, Paris 75015, France 5 Viral Diseases Branch, Walter Reed Army Institute of Research, Silver Spring, MD, 20910, USA. 6 Department of Medicine, Upstate Medical University of New York, Syracuse, New York, NY, 13210, USA 7 Queen Sirikit National Institute of Child Health, Bangkok, Thailand 8 National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand 9 Department of Virology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand 10 Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand 11 International Vaccine Institute, Seoul, South Korea 12 Department of Biology, University of Florida, Gainesville, FL 32610, USA 13 Emerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA
คำสำคัญ (EN):	host population size
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science