คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Sittiporn Parnmen

เผยแพร่โดย

1 Toxicology Center, National Institute of Health, Department of Medical Sciences, Ministry of Public Health 2 Department of Biology, Natural Medicinal Mushroom Museum, Mahasarakham University 3 Department of Biology, Faculty of Science, Srinakharinwirot University, Thailand

เผยแพร่เมื่อ ไม่ระบุวันที่เผยแพร่

หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Group B Streptococcal bacteremia burden and trends over time, 2007-15, Thailand Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand Wolbachia supergroups A and B in natural populations of medically important filth flies (Diptera : Muscidae, Calliphoridae, and Sarcophagidae) in Thailand Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand Prevalent emm types and superantigen gene patterns of group A Streptococcus in Thailand. Draft Genome Sequence of a Clostridium botulinum Isolate from Thailand Harboring the Subtype bont/B8 Gene Characterization and identification of Hb Bart's hydrops fetalis caused by a compound heterozygous mutation --SEA /--CR , a novel α0 -thalassemia deletion Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Mangrove forests in Thailand Progress on Rubber Breeding of Thailand

คัดลอก URL

ชื่อเรื่อง (EN):	DNA barcoding for identification of poisonous mushrooms from 187 cases of mycetism in Thailand
ผู้แต่ง / หัวหน้าโครงการ (EN):	Sittiporn Parnmen
บทคัดย่อ (EN):	Purpose: Epidemiological data showed increasing incidence rates of mushroom poisoning cases in Thailand. This study aimed to identify mushroom samples from 187 clinically reported cases during 2012 to 2019 based on DNA barcoding and also determine their toxins. Methods: Clinical mushroom samples were identified using DNA sequence data under the selected phylogenetic criterion and DNA barcoding analysis. Mushroom toxins were analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) with multiple reaction monitoring (MRM) as well as liquid chromatography quadrupole time-of-flight mass spectrometry (LC-QTOF-MS). Results and conclusions: Our results revealed that gastrointestinal irritant mushroom poisoning was most frequently encountered, followed by other types of mushroom poisoning, including neurotoxic, cytotoxic, myotoxic and metabolic/endocrine toxicity. More than 80% of poisoning cases occurred in rainy season extending from May to August. Most commonly found wild mushrooms were Amanita brunneitoxicaria, A. exitialis, A. fuliginea, Cantharocybe virosa, Chlorophyllum molybdites, C. globosum, Entoloma sp., Inocybe sp., Leccinellum sp., Russula subnigricans and Xerocomus sp. These included three main lethal species; A. brunneitoxicaria, A. exitialis and R. subnigricans. The toxins discovered from the clinical samples were alkaloid muscarine, alpha-amanitin, beta-amanitin, phallacidin, phalloidin, allenic norleucine, coprine & cycloprop-2-ene carboxylic acid. These cases of mycetism occurred mainly due to misidentification and misconceptions about indigenous knowledge of the nontoxic and toxic mushrooms.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=701
เผยแพร่โดย (EN):	1 Toxicology Center, National Institute of Health, Department of Medical Sciences, Ministry of Public Health 2 Department of Biology, Natural Medicinal Mushroom Museum, Mahasarakham University 3 Department of Biology, Faculty of Science, Srinakharinwirot University, Thailand
คำสำคัญ (EN):	Thailand
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science