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Characterization of an unusual DS-1-like G8P[8] rotavirus strain from Japan in 2017: evolution of emerging DS-1-like G8P[8] strains through reassortment
Hajime Kamiya - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Characterization of an unusual DS-1-like G8P[8] rotavirus strain from Japan in 2017: evolution of emerging DS-1-like G8P[8] strains through reassortment
ผู้แต่ง / หัวหน้าโครงการ (EN): Hajime Kamiya
บทคัดย่อ (EN): The emergence of unusual DS-1-like intergenogroup reassortant rotaviruses having the bovine-like G8 genotype (DS-1-like G8P[8] strains) has been reported from several Asian countries. During the rotavirus surveillance program in Japan in 2017, a DS-1-like G8P[8] strain (RVA/Human-wt/JPN/SO1162/2017/G8P[8]) was identified in 43 rotavirus-positive stool samples. Strain SO1162 was shown to have a unique genotype constellation including both genogroup 1 and 2 genes: G8-P[8]-I2-R2-C2-M2-A2-N2-T2-E2-H2. Phylogenetic analysis revealed that the VP1 gene of strain SO1162 appeared to have originated from DS-1- like G1P[8] strains from Thailand and Vietnam, while the remaining 10 genes were closely related to those of the previously reported DS-1-like G8P[8] strains. Thus, strain SO1162 was suggested to be a reassortant that acquired the VP1 gene from Southeast Asian DS-1-like G1P[8] strains on the genetic background of co-circulating DS-1-like G8P[8] strains. Our findings will provide important insights into the evolutionary dynamics of emerging DS-1- like G8P[8] strains.
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ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=552
เผยแพร่โดย (EN): 1 Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Shinjuku, Tokyo 162-8640, Japan. 2 Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan. 3 National Institute of Health, Department of Medical Sciences, Nonthaburi 11000, Thailand. 4 Institute for Clinical Research, National Mie Hospital, Tsu, Mie 514-0125, Japan. 5 Department of Pediatrics, Kawasaki Medical School, Okayama, Okayama 700-8505, Japan. 6 Department of Pediatrics, National Mie Hospital, Tsu, Mie 514-0125, Japan. 7 Umemoto Children’s Clinic, Tsu, Mie 514-0004, Japan. 8 Sotobo Children’s Clinic, Isumi, Chiba 299-4503, Japan. 9 Department of Pediatrics, Kameda Medical Center, Kamogawa, Chiba 296-8602, Japan. 10 Department of Pediatrics, Mie Chuo Medical Center, Tsu, Mie 514-1101, Japan. 11 Department of Pediatrics, Japanese Red Cross Ise Hospital, Ise, Mie 516-8512, Japan.
คำสำคัญ (EN): DS-1-like G8P[8] strains; DS-1-like intergenogroup reassortant strains; group A rotavirus; whole genomic analysis
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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Characterization of an unusual DS-1-like G8P[8] rotavirus strain from Japan in 2017: evolution of emerging DS-1-like G8P[8] strains through reassortment
Hajime Kamiya
1 Infectious Disease Surveillance Center, National Institute of Infectious Diseases, Shinjuku, Tokyo 162-8640, Japan. 2 Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan. 3 National Institute of Health, Department of Medical Sciences, Nonthaburi 11000, Thailand. 4 Institute for Clinical Research, National Mie Hospital, Tsu, Mie 514-0125, Japan. 5 Department of Pediatrics, Kawasaki Medical School, Okayama, Okayama 700-8505, Japan. 6 Department of Pediatrics, National Mie Hospital, Tsu, Mie 514-0125, Japan. 7 Umemoto Children’s Clinic, Tsu, Mie 514-0004, Japan. 8 Sotobo Children’s Clinic, Isumi, Chiba 299-4503, Japan. 9 Department of Pediatrics, Kameda Medical Center, Kamogawa, Chiba 296-8602, Japan. 10 Department of Pediatrics, Mie Chuo Medical Center, Tsu, Mie 514-1101, Japan. 11 Department of Pediatrics, Japanese Red Cross Ise Hospital, Ise, Mie 516-8512, Japan.
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Reassortment of Human and Animal Rotavirus Gene Segments in Emerging DS-1- Like G1P[8] Rotavirus Strains Full Genome Characterization of Novel DS-1-Like G8P[8] Rotavirus Strains that Have Emerged in Thailand: Reassortment of Bovine and Human Rotavirus Gene Segments in Emerging DS-1-Like Intergenogroup Re Emergence and Characterization of Unusual DS-1-Like G1P[8] Rotavirus Strains in Children with Diarrhea in Thailand Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand Whole genomic analysis of bovine group A rotavirus strains A5-10 and A5-13 provides evidence for close evolutionary relationship with human rotaviruses Full genomic analysis of a human G9P[23] rotavirus strain from a child with diarrhea in Thailand Characterization of chikungunya virus-like particles Characterization of Chikungunya Virus-Like Particles Whole Genomic Analysis of an Unusual Human G6P[14] Rotavirus Strain Isolated from a Child with Diarrhea in Thailand: Evidence for Bovine-To-Human Interspecies Transmission and Reassortment Events VDO แนะนำบริการ สำหรับภาคเอกชน Japan Version
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