สืบค้นงานวิจัย
Biofilm production and antifungal susceptibility of co-cultured Malassezia pachydermatis and Candida parapsilosis isolated from canine seborrheic dermatitis
K. Bumroongthai - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Biofilm production and antifungal susceptibility of co-cultured Malassezia pachydermatis and Candida parapsilosis isolated from canine seborrheic dermatitis
ผู้แต่ง / หัวหน้าโครงการ (EN): K. Bumroongthai
บทคัดย่อ (EN): The yeasts Malassezia (M.) pachydermatis and Candida (C.) parapsilosis are often coisolated in case of canine seborrhea dermatitis (SD) and also are emerging as opportunistic pathogens of immunocompromised human beings. Increased information about how their relationship results in biofilm production and an antifungal response would be useful to inform treatment and control. This study was designed to investigate biofilm production derived from co-culture of M. pachydermatis and C. parapsilosis from dog skin and to determine their in vitro antifungal susceptibility. We demonstrated that regardless of yeast strain or origin all single and dual cultures produced biofilms within 24 hours, and the greatest amount was present after 72 hours. Biofilm production from mixed cultures was greater than for single strains (P < .05). All sessile forms of the single and dual cultures were resistant to the tested antifungals itraconazole and ketoconazole, whereas planktonic forms were susceptible. The study suggests that dual cultures produce stronger biofilms that are likely to enhance persistence in skin lesions in dogs and result in greater resistance to antifungal treatment.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=491
เผยแพร่โดย (EN): 1 Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330 2 Department of Medical Science, National Institute of Medical Science, Bangkok, 11000 3 Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330 Thailand
คำสำคัญ (EN): dogs.
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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Biofilm production and antifungal susceptibility of co-cultured Malassezia pachydermatis and Candida parapsilosis isolated from canine seborrheic dermatitis
K. Bumroongthai
1 Department of Veterinary Microbiology, Faculty of Veterinary Science, Chulalongkorn University, Bangkok 10330 2 Department of Medical Science, National Institute of Medical Science, Bangkok, 11000 3 Department of Microbiology, Faculty of Medicine, Chulalongkorn University, Bangkok 10330 Thailand
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