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Bioaccumulation of DDT Residues in Human Serum: an Historical Use of DDT Indoor Residual Spraying in Malaria Endemic Regions of Thailand
Punthip Teeyapant - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Bioaccumulation of DDT Residues in Human Serum: an Historical Use of DDT Indoor Residual Spraying in Malaria Endemic Regions of Thailand
ผู้แต่ง / หัวหน้าโครงการ (EN): Punthip Teeyapant
บทคัดย่อ (EN): In Thailand, DDT indoor residual spraying (IRS) was used to interrupt malaria transmission until it was phased out between 1995 and 1999. However, contamination by DDT and its primary metabolite, p,p´-DDE remains a serious environmental and human health concern. We investigated serum concentrations of p,p´-DDE and p,p´-DDT in Southern Thai residents living in malaria-endemic areas where IRS with DDT was applied. Levels of p,p´-DDE and p,p´-DDT were measured in plasma serum of 346 participants (205 females, 141 males) from Southern provinces of Thailand and from Bangkok. Serum concentrations of measured compounds were signifcantly higher in Southern Thai residents than general population (in Bangkok) (P < 0.001). The highest geometric mean value of p,p´-DDE was 6,531 (95% CI=4,083-8,979) and 5,053 (95% CI=2,909-7,197) ng/g lipids in female and male subjects, respectively. Even though, DDT ultimately is banned for all uses, the concentration of the daughter compound p,p´-DDE was much higher in Southern subjects than in the general population. A high ratio of p,p´-DDE/p,p´-DDT indicates that the exposure is due to past rather than recent use of DDT.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=445
เผยแพร่โดย (EN): Division of Toxicology, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand
คำสำคัญ (EN): Bioaccumulation; DDT ratio; indoor residual spraying; serum concentrations; Thailand
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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การอ้างอิง

Punthip Teeyapant. "Bioaccumulation of DDT Residues in Human Serum: an Historical Use of DDT Indoor Residual Spraying in Malaria Endemic Regions of Thailand". ไม่ระบุหน่วยงาน. ม.ป.ป.

Punthip Teeyapant. "Bioaccumulation of DDT Residues in Human Serum: an Historical Use of DDT Indoor Residual Spraying in Malaria Endemic Regions of Thailand". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Bioaccumulation of DDT Residues in Human Serum: an Historical Use of DDT Indoor Residual Spraying in Malaria Endemic Regions of Thailand
Punthip Teeyapant
Division of Toxicology, Department of Medical Sciences, Ministry of Public Health, Nonthaburi 11000, Thailand
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