คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Ratana Tacharoenmuang

เผยแพร่โดย

1 National Institute of Health, Department of Medical Sciences, Nonthaburi 11000, Thailand 2 Bureau of Epidemiology, Department of Diseases Control, Nonthaburi 11000, Thailand.

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หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand Group B Streptococcal bacteremia burden and trends over time, 2007-15, Thailand Wolbachia supergroups A and B in natural populations of medically important filth flies (Diptera : Muscidae, Calliphoridae, and Sarcophagidae) in Thailand Draft Genome Sequence of a Clostridium botulinum Isolate from Thailand Harboring the Subtype bont/B8 Gene Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Mangrove forests in Thailand Progress on Rubber Breeding of Thailand Elsholtzia (Lamiaceae) in Thailand An Outbreak of Acute Hepatitis Caused by Genotype IB Hepatitis A Viruses Contaminating the Water Supply in Thailand Human rotavirus surveillance in hospitalized gastroenteritis cases in Bangkok, Thailand during 2015 - 2018

คัดลอก URL

ชื่อเรื่อง (EN):	Rotavirus outbreak in adults, Thailand 2018
ผู้แต่ง / หัวหน้าโครงการ (EN):	Ratana Tacharoenmuang
บทคัดย่อ (EN):	Group A rotaviruses (RVA) are the leading cause of severe diarrhea in infants and young children worldwide. It is estimated that rotaviruses are associated to 215,000 deaths in the children younger than 5 years, especially in developing countries in Africa and Asia [Tate et al., 2016]. RVA belongs to the family Reoviridae, the rotavirus genome consists of 11 segments of double-stranded RNA(dsRNA), encoding six structural proteins (VP1-VP4, VP6 and VP7) and five non-structural proteins (NSP1-NSP5/6). A binary genotype classification system based on the outer capsid proteins VP7 and VP4 are used in molecular epidemiology [Estes et al., 2007]. Currently, RVAs have been classified into 27G types and 37P types [Matthijnssens et al., 2011]. The most prevalent genotypes of RVA worldwide were G1P[8], G2P[4], G3P[8], G4P[8], G9P[8] and G12P[8] [WHO, 2015]. In Thailand, the RVA detection rate in hospitalized children with gastroenteritis ranges 28.4 to 44.5% [Maneekarn et al., 2014]. However, older children and adults also can get sick from RVAs. Interestingly, the hospitalized gastroenteritis with RVA in Thailand tend to be older children and adults in 2018. Between January and March 2018, there are 153 stool and 12 vomitus specimens were collected from hospitalized gastroenteritis cases, totally 165 specimens were sent to Enteric Viruses Section laboratory at Thai-NIH in a reverse cold-chain condition. All specimens subjected to conventional RT-PCR to assign their GP types. The results shown that the RVA was detected in 115/165 (69.7%) gastroenteritis case specimens. The G3P[8] (24.4%) was the predominant genotype, followed by G2P[4] (22.1%), G9P[8] (14.5%), G1P[6] (10.7%), G1P[8] (7.6%), G3P[6] (3.1%), G3P[4] (2.3%), and G8P[8] (2.3%). The prevalence of RVAs infection was in gastroenteritis cases aged 28 years old, while the average age of gastroenteritis cases was 27 years old. The occurrence of RVA gastroenteritis in adults is not common, however there has been reported the RVAs gastroenteritis cases in older children and adults in India and China [Anandan et al., 2014; Wang et al., 2017]. This study demonstrates RVAs gastroenteritis was increased in older children and adults, and the unusual G1P[6] RVAs have been found in this study. The precise genome profiles will also be presented by whole genome nucleotide sequence determination.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=668
เผยแพร่โดย (EN):	1 National Institute of Health, Department of Medical Sciences, Nonthaburi 11000, Thailand 2 Bureau of Epidemiology, Department of Diseases Control, Nonthaburi 11000, Thailand.
คำสำคัญ (EN):	Gastroenteritis
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science