คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Kriangsak Ruchusatsawat

เผยแพร่โดย

1 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand. 2 Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. 3 Department of Biology, and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. 4 Mathematical Modelling of Infectious Diseases Unit, Institute Pasteur, UMR2000, CNRS, Paris, France. 5 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.

เผยแพร่เมื่อ ไม่ระบุวันที่เผยแพร่

หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Whole-genome sequence analysis of Zika virus isolated from the plasma of an infected patient in Thailand Antibody response to Zika and Dengue virus among the Zika realtime PCR positive cases in Thailand, 2016 Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Development of the cost and time saving Zika virus detection method by real time RT-PCR in response for 2016 outbreak in Thailand Development and evaluation of multiplex real-time RT-PCR for Dengue, Chikungunya and Zika virus detection in Thailand Monitoring arbovirus in Thailand: Surveillance of dengue, chikungunya and zika virus, with a focus on coinfections จีโนมของไวรัสซิกาที่ติดเชื้อในยุงรำคาญจากการเพาะเลี้ยงในห้องปฏิบัติการโดย Next-generation sequencing Complete genome sequences of Zika virus from infected laboratory strains of Culex quinquefasciatus Zika Incidence among Patients with Suspected Dengue Fever (Preliminary Report) Ecotourism is a significant tool for sustainable tourist attraction: A case study of Khao Krajome, Ratchaburi province, Thailand Increasing Growth Opportunities for Non-heavy and Heavy Users–A Case Study of Yogurt Cups in Thailand

คัดลอก URL

ชื่อเรื่อง (EN):	Long-term circulation of Zika virus in Thailand: an observational study
ผู้แต่ง / หัวหน้าโครงการ (EN):	Kriangsak Ruchusatsawat
บทคัดย่อ (EN):	Background: Little is known about the historical and current risk of Zika virus infection in southeast Asia, where the mosquito vector is widespread and other arboviruses circulate endemically. Centralised Zika virus surveillance began in Thailand in January, 2016. We assessed the long-term circulation of Zika virus in Thailand. Methods: In this observational study, we analysed data from individuals with suspected Zika virus infection who presented at hospitals throughout the country and had biological samples (serum, plasma, or urine) tested for confirmation with PCR at the National Institute of Health laboratories in Bangkok. We analysed the spatial and age distribution of cases, and constructed time-resolved phylogenetic trees using genomes from Thailand and elsewhere to estimate when Zika virus was first introduced. Findings: Of the 3089 samples from 1717 symptomatic individuals tested between January, 2016, and December, 2017, 368 were confirmed to have Zika virus infection. Cases of Zika virus infection were reported throughout the year, and from 29 of the 76 Thai provinces. Individuals had 2.8 times (95% CI 2.3–3.6) the odds of testing positive for Zika virus infection if they came from the same district and were sick within the same year of a person with a confirmed infection relative to the odds of testing positive anywhere, consistent with focal transmission. The probability of cases being younger than 10 years was 0.99 times (0.72–1.30) the probability of being that age in the underlying population. This probability rose to 1.62 (1.33–1.92) among those aged 21–30 years and fell to 0.53 (0.40–0.66) for those older than 50 years. This age distribution is consistent with that observed in the Zika virus epidemic in Colombia. Phylogenetic reconstructions suggest persistent circulation within Thailand since at least 2002. Interpretation: Our evidence shows that Zika virus has circulated at a low but sustained level for at least 16 years, suggesting that Zika virus can adapt to persistent endemic transmission. Health systems need to adapt to cope with regular occurrences of the severe complications associated with infection.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=550
เผยแพร่โดย (EN):	1 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand. 2 Department of Medicine, University of California, San Francisco, San Francisco, CA, USA. 3 Department of Biology, and Emerging Pathogens Institute, University of Florida, Gainesville, FL, USA. 4 Mathematical Modelling of Infectious Diseases Unit, Institute Pasteur, UMR2000, CNRS, Paris, France. 5 Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
คำสำคัญ (EN):	Long-term circulation
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science