คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Tharmaphornpilas

เผยแพร่โดย

1 Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand 2 Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand. 3 Faculty of Pharmacy, Mahidol University, Bangkok, Thailand. 4 Phetchabun Provincial Health Office, Phetchabun, Thailand. 5 Sukhothai Provincial Health Office, Sukhothai, Thailand. 6 Department of Medical Science, Ministry of Public Health, Nonthaburi, Thailand. 7 Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.

เผยแพร่เมื่อ ไม่ระบุวันที่เผยแพร่

หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand Group B Streptococcal bacteremia burden and trends over time, 2007-15, Thailand Wolbachia supergroups A and B in natural populations of medically important filth flies (Diptera : Muscidae, Calliphoridae, and Sarcophagidae) in Thailand Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand Draft Genome Sequence of a Clostridium botulinum Isolate from Thailand Harboring the Subtype bont/B8 Gene Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Emergence and Characterization of Unusual DS-1-Like G1P[8] Rotavirus Strains in Children with Diarrhea in Thailand Mangrove forests in Thailand Progress on Rubber Breeding of Thailand Molecular Characterization of Clostridium botulinum Isolates from Foodborne Outbreaks in Thailand, 2010

คัดลอก URL

ชื่อเรื่อง (EN):	Evaluating the first introduction of rotavirus vaccine in Thailand : Moving from evidence to policy
ผู้แต่ง / หัวหน้าโครงการ (EN):	Tharmaphornpilas
บทคัดย่อ (EN):	Background: We assessed the effectiveness and possible impact of introducing rotavirus vaccine into the routine immunization program. Methods: Two provinces were selected for an observational study, one where vaccine was introduced and another where vaccine was not available. In these areas, two sub-studies were linked. The prospective cohort study enrolled children 2month old and followed them to the age of 18months to detect all diarrhea episodes. The hospital surveillance study enrolled all children up to age 5 hospitalized with diarrhea whose fecal samples were tested for rotavirus. Rates of rotavirus hospitalizations in older children who had not been vaccinated in both settings provided data to determine whether immunization had an indirect herd effect. The key endpoints for the study were both vaccine effectiveness (VE) based upon hospitalized rotavirus diarrhea and herd protection. Findings: From the cohort study, the overall VE for hospitalized rotavirus diarrhea was 88% (95%CI 76-94). Data from hospital surveillance indicated that for 2 consecutive years, the seasonal peak of rotavirus admissions was no longer present in the vaccinated area. Herd protection was observed among older children born before the rotavirus vaccine program was introduced, who experienced a 40-69% reduction in admission for rotavirus. Conclusions: Rotavirus vaccine was highly effective in preventing diarrheal hospitalizations and in conferring herd protection among older children who had not been vaccinated.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=505
เผยแพร่โดย (EN):	1 Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand 2 Department of Disease Control, Ministry of Public Health, Nonthaburi, Thailand. 3 Faculty of Pharmacy, Mahidol University, Bangkok, Thailand. 4 Phetchabun Provincial Health Office, Phetchabun, Thailand. 5 Sukhothai Provincial Health Office, Sukhothai, Thailand. 6 Department of Medical Science, Ministry of Public Health, Nonthaburi, Thailand. 7 Fogarty International Center, National Institutes of Health, Bethesda, MD, USA.
คำสำคัญ (EN):	Rotavirus vaccine; Vaccine effectiveness; Vaccine impact
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science