สืบค้นงานวิจัย
Inhibitions of key enzymes relevant to obesity and diabetes of thai local mushroom extracts
Pongkunakorn T. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Inhibitions of key enzymes relevant to obesity and diabetes of thai local mushroom extracts
ผู้แต่ง / หัวหน้าโครงการ (EN): Pongkunakorn T.
บทคัดย่อ (EN): The aim of this experiment was to determine inhibitory activities against lipase (anti-obesity property) as well as α-amylase and α-glucosidase (anti-diabetic property) of fifteen Thai local mushroom extracts including Kai-khao (Russula sp.), Kai-kiew (Russula sp.), Nha-lae (Russula sp.), Sa-med (Boletus sp.), E-tun (Russula aff. sp.), Ra-ngok-khao (Amanita aff. sp.), Kor-kar-dang (Russula sp.), Por-nung (Astraeus sp.), Por-fai (Astraeus sp.), Ra-ngok-luang (Amanita sp.), Kor-kar-khao (Russula sp.), Nam-mak (Macowanites sp.), Koh-noi (Russula aff. sp.), Din-khao (Russula sp.) and Khao-pang (Russula sp.) in Amnat-Charoen province, Thailand. All mushrooms were extracted using ddH 2 O (20 mg/mL) in a 50°C water bath shaker for 8 hrs. The enzyme inhibitory activities were performed using a colorimetric microplate assay. The results showed that anti-lipase activities of mushroom extracts (4 mg/mL) were in the range of 12-77% inhibition. Din-khao mushroom exhibited the highest inhibition, while Por-fai and Por-nung mushrooms exhibited the lowest. The anti-α-glucosidase activities of mushroom extracts (5 mg/mL) were in the range of 10-79% inhibition. Sa-med mushroom exhibited the highest inhibition, while Kor-kar-dang mushroom exhibited the lowest. However, the inhibition of α-amylase could not be detected in this study. These findings are useful for potential health promotion for Thai local mushroom consumption in controlling obesity and diabetes through key enzymes inhibition. © 2017, King Mongkut's Institute of Technology Ladkrabang. All rights reserved.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85064317551&partnerID=40&md5=1c7ba2567f55e7c7847ca22d47a37429
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Thai local mushroom
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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Inhibitions of key enzymes relevant to obesity and diabetes of thai local mushroom extracts
Pongkunakorn T.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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