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The prevalence and genotype diversity of Human Rotavirus A circulating in Thailand, 2011-2014
Chieochansin T. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): The prevalence and genotype diversity of Human Rotavirus A circulating in Thailand, 2011-2014
ผู้แต่ง / หัวหน้าโครงการ (EN): Chieochansin T.
บทคัดย่อ (EN): Human rotavirus A (RVA) is the major infectious virus causing acute watery diarrhea in children, especially those younger than 5 years of age, and is a major public health problem in Thailand. Outbreaks of this virus have been reported worldwide. Besides the common genotypes, unusual genotypes providing evidence of inter-species transmission have also been described. Therefore, the aim of this study was to investigate the prevalence and genotypes of RVA in Thailand. A total of 688 samples were collected from children who were hospitalized with acute diarrhea in Chumphae Hospital in Khon Kaen and Chulalongkorn Hospital in Bangkok. RVA was detected using one-step RT-PCR and the genotypes were evaluated by sequencing. Overall, 204 of the 688 samples (30%) were positive for RVA. Nine genotypes were identified: three common in humans (G1P[8] [53%], G2P[4] [18%], G3P[8] [12%]), one feline-like (G3P[9] [1%]), four porcine-like (G4P[6] [0.5%], G5P[6] [0.5%], G9P[8] [0.5%], G12P[6] [1.5%]), and one bovine-like (G8P[8] [13%]). The variation in virus genotypes and the animal-like genotypes detected in this study suggested that a high diversity of RVA types is circulating in the Thai population. Therefore, continuous molecular epidemiological monitoring of RVA is essential and has implications for the national vaccination program. © 2015 Elsevier B.V.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84947717569&doi=10.1016%2fj.meegid.2015.11.011&partnerID=40&md5=dfd026db8e4d0c2a087a80aaf34905ae
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Thailand
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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The prevalence and genotype diversity of Human Rotavirus A circulating in Thailand, 2011-2014
Chieochansin T.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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