สืบค้นงานวิจัย
Effects of malaria parasite density on blood cell parameters
Kotepui M. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Effects of malaria parasite density on blood cell parameters
ผู้แต่ง / หัวหน้าโครงการ (EN): Kotepui M.
บทคัดย่อ (EN): Changes in blood cell parameters are already a well-known feature of malarial infections. To add to this information, the objective of this study was to investigate the varying effects that different levels of parasite density have on blood cell parameters. Patients diagnosed with malaria at Phobphra Hospital, Tak Province, Thailand between January 1st 2009 and January 1st 2012 were recruited as subjects for data collection. Blood cell parameters of 2,024 malaria-infected patients were evaluated and statistically analyzed. Neutrophil and platelet counts were significantly higher, however, RBC count was significantly lower in patients with P. falciparum infection compared to those with P. vivax infection (p<0.0001). Leukocyte counts were also significantly higher in patients with high parasitemia compared to those with low and moderate parasitemia. In terms of differential leukocyte count, neutrophil count was significantly higher in patients with high parasitemia compared to those with low and moderate parasitemia (p<0.0001). On the other hand, both lymphocyte and monocyte counts were significantly lower in patients with high parasitemia (p<0.0001). RBC count and Hb concentration, as well as platelet count were also significantly reduced (p<0.05) and (p<0.0001), respectively. To summarize, patients infected with different malaria parasites exhibited important distinctive hematological parameters, with neutrophil and eosinophil counts being the two hematological parameters most affected. In addition, patients infected with different malarial densities also exhibited important changes in leukocyte count, platelet count and hemoglobin concentration during the infection. These findings offer the opportunity to recognize and diagnose malaria related anemia, help support the treatment thereof, as well as relieve symptoms of severe malaria in endemic regions. © 2015 Kotepui et al.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84926052374&doi=10.1371%2fjournal.pone.0121057&partnerID=40&md5=1b503910fde18128a0a90c09a68694be
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Young Adult
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
หากไม่พบเอกสารฉบับเต็ม (Full Text) โปรดติดต่อหน่วยงานเจ้าของข้อมูล

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Kotepui M.. "Effects of malaria parasite density on blood cell parameters". ไม่ระบุหน่วยงาน. ม.ป.ป.

Kotepui M.. "Effects of malaria parasite density on blood cell parameters". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Effects of malaria parasite density on blood cell parameters
Kotepui M.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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