สืบค้นงานวิจัย
Characteristics and associated factors of acute kidney injury among adult dengue patients: A retrospective single-center study
Diptyanusa A. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Characteristics and associated factors of acute kidney injury among adult dengue patients: A retrospective single-center study
ผู้แต่ง / หัวหน้าโครงการ (EN): Diptyanusa A.
บทคัดย่อ (EN): Severe dengue cases have been increasingly reported in Thailand, and the under-reporting of acute kidney injury (AKI) in cases of dengue viral infection has become an obstacle in obtaining an accurate description of the true nature and epidemiology of AKI. Because AKI may lead to patient morbidity and mortality, an early diagnosis is important in preventing its onset in dengue patients. This study aimed to determine the prevalence, clinical and laboratory characteristics, and associated factors of AKI among adult dengue patients. This retrospective study reviewed admission data from the medical records of adult dengue patients admitted to the Bangkok Hospital for Tropical Diseases between January 2012 and November 2017 and stratified these patients into AKI and non-AKI groups using the Kidney Disease Improving Global Outcomes criteria (KDIGO). A total of 1,484 patients were included in the study, with 71 categorized into the AKI group. The prevalence of AKI was 4.8%. In the AKI group, the predominant age range was 18–40 years (71.8%), with a female to male ratio of 1:2.7. These patients showed significantly (P < 0.05) higher proportions of altered consciousness, dyspnea, low mean arterial blood pressure, high-grade fever, major bleeding, severe thrombocytopenia, hypoalbuminemia, severe transaminitis, coagulopathy, metabolic acidosis, rhabdomyolysis, proteinuria, hematuria, and pyuria. Our study established that older age, male sex, diabetes mellitus, obesity, severe dengue, and coexisting bacterial infection were significant associated factors for AKI in dengue by multivariate analysis. A total of 10 (14.1%) patients with AKI received dialysis, among which 9 (12.7%) patients from the AKI group died. Our findings suggest that an awareness of AKI, its early diagnosis, and evaluation of clinical and laboratory characteristics of dengue patients will help clinicians to initiate appropriate therapy for dengue-associated AKI. © 2019 Diptyanusa et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059641680&doi=10.1371%2fjournal.pone.0210360&partnerID=40&md5=6efc198fae630c4f79d089f6b7a3d1ac
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): unconsciousness
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
หากไม่พบเอกสารฉบับเต็ม (Full Text) โปรดติดต่อหน่วยงานเจ้าของข้อมูล

การอ้างอิง

Diptyanusa A.. "Characteristics and associated factors of acute kidney injury among adult dengue patients: A retrospective single-center study". ไม่ระบุหน่วยงาน. ม.ป.ป.

Diptyanusa A.. "Characteristics and associated factors of acute kidney injury among adult dengue patients: A retrospective single-center study". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Characteristics and associated factors of acute kidney injury among adult dengue patients: A retrospective single-center study
Diptyanusa A.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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