สืบค้นงานวิจัย
Serosurveillance for pandemic influenza A (H1N1) 2009 virus infection in domestic elephants, Thailand
Paungpin W. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Serosurveillance for pandemic influenza A (H1N1) 2009 virus infection in domestic elephants, Thailand
ผู้แต่ง / หัวหน้าโครงการ (EN): Paungpin W.
บทคัดย่อ (EN): The present study conducted serosurveillance for the presence of antibody to pandemic influenza A (H1N1) 2009 virus (H1N1pdm virus) in archival serum samples collected between 2009 and 2013 from 317 domestic elephants living in 19 provinces situated in various parts of Thailand. To obtain the most accurate data, hemagglutination-inhibition (HI) assay was employed as the screening test; and sera with HI antibody titers 20 were further confirmed by other methods, including cytopathic effect/hemagglutination based-microneutralization (microNT) and Western blot (WB) assays using H1N1pdm matrix 1 (M1) or hemagglutinin (HA) recombinant protein as the test antigen. Conclusively, the appropriate assays using HI in conjunction with WB assays for HA antibody revealed an overall seropositive rate of 8.5% (27 of 317). The prevalence of antibody to H1N1pdm virus was 2% (4/172) in 2009, 32% (17/53) in 2010, 9% (2/22) in 2011, 12% (1/8) in 2012, and 5% (3/62) in 2013. Notably, these positive serum samples were collected from elephants living in 7 tourist provinces of Thailand. The highest seropositive rate was obtained from elephants in Phuket, a popular tourist beach city. Young elephants had higher seropositive rate than older elephants. The source of H1N1pdm viral infection in these elephants was not explored, but most likely came from close contact with the infected mahouts or from the infected tourists who engaged in activities such as elephant riding and feeding. Nevertheless, it could not be excluded that elephant-to-elephant transmission did occur. © 2017 Paungpin et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85032512450&doi=10.1371%2fjournal.pone.0186962&partnerID=40&md5=3e6514b3b39d7b8ba906f39cdb3c9528
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Thailand
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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การอ้างอิง

Paungpin W.. "Serosurveillance for pandemic influenza A (H1N1) 2009 virus infection in domestic elephants, Thailand". ไม่ระบุหน่วยงาน. ม.ป.ป.

Paungpin W.. "Serosurveillance for pandemic influenza A (H1N1) 2009 virus infection in domestic elephants, Thailand". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Serosurveillance for pandemic influenza A (H1N1) 2009 virus infection in domestic elephants, Thailand
Paungpin W.
มหาวิทยาลัยมหิดล
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