คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Benjawan Phetsuksiri

เผยแพร่โดย

1 Ministry of Public Health, National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand. 2 Ministry of Public Health, Department of Disease Control, Bureau of Tuberculosis, Bangkok, Thailand.

เผยแพร่เมื่อ ไม่ระบุวันที่เผยแพร่

หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ QuantiFERON-TB Gold In-Tube Test for Tuberculosis Prevention in HIV-Infected Patients Tuberculin skin test and QuantiFERON-TB Gold In-tube Test for latent tuberculosis in Thai HIV-infected adults Tuberculin skin test and QuantiFERON®-TB Gold In-tube Test for diagnosing latent tuberculosis infection among Thai healthcare workers QuanFERON®-TB GOLD in-tUBE test for diagnosing latent tuberculosis infection among clinical-year Thai medical students ใช้เทคนิค ELISA test kit ในภาคเกษตรกร T-SPOT.TB test ในการตรวจวินิจฉัยการติดเชื้อวัณโรคและติดตามการรักษาแบบป้องกันในกลุ่มบุคลากรทางการแพทย์ T-SPOT.TB test for detecting Mycobacterium tuberculosis infection and monitoring the prophylactic Risk factors for multidrug-resistant tuberculosis among patients with pulmonary tuberculosis at the central chest institute of Thailand T-SPOT.TB test and clinical risk scoring for diagnosis of latent tuberculosis infection among Thai healthcare workers T-SPOT®.TB test and clinical risk scoring for diagnosis of latent tuberculosis infection among Thai healthcare workers. T‑SPOT®.TB Test for Latent Tuberculosis infection Diagnosis and Treatment Guidance in Thai Health‑Care Professionals

คัดลอก URL

ชื่อเรื่อง (EN):	QuantiFERON-TB Gold In-Tube test in active tuberculosis patients and healthy adults
ผู้แต่ง / หัวหน้าโครงการ (EN):	Benjawan Phetsuksiri
บทคัดย่อ (EN):	Interferon-gamma (IFN- Y) release assays have improved latent tuberculosis (TB) detection and have been considered promising for the diagnosis of TB disease. However, diagnosis efficacy data is limited in high burden countries. The aim of this study was to determine the diagnostic potential of the QuantiFERON-TB Gold In-Tube (QFT-GIT) test for the diagnosis of active TB in an endemic setting for TB. A cross-sectional study was conducted in a group of 102 Thai patients with clinical symptoms and chest x-ray findings suggesting of active pulmonary TB and a group of 112 healthy adults. Testing was carried out using sputum microscopy, mycobacterial culture and QFT-GIT test. Of these patients, QFT-GIT was positive in 73 (71.57%), negative in 27 (26.47%), and undetermined in 2 (1.96%) cases. Among healthy controls, QFT-GIT was positive in 18 (16.07%), negative in 93 (83.04%), and undetermined in 1 (0.89%) person. Based on TB culture results, the sensitivity of QFTGIT for diagnosing active TB was 84.21% (95% confidence interval (CI); 72.13-92.52). The positive and negative predictive values were 65.75% (95% CI; 59.26-71.70) and 66.67% (95% CI; 49.94-80.04), respectively. The median IFN- Y level in culture-confirmed TB patients was 3.91 compared to 0.03 IU/mL of the healthy group. QFT-GIT appears to be a useful indirect test for TB diagnosis in Thailand and its use is recommended in association with clinical and radiological assessments for identifying active or latent TB.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=540
เผยแพร่โดย (EN):	1 Ministry of Public Health, National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand. 2 Ministry of Public Health, Department of Disease Control, Bureau of Tuberculosis, Bangkok, Thailand.
คำสำคัญ (EN):	Active tuberculosis; Latent tuberculosis; Diagnosis; QuantiFERON; Interferon-gamma release assay; IGRA
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science