คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง THANA KHAWCHAROENPORN

เผยแพร่โดย

1 Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathumthani 2 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand, 3 LM Mundy, GlaxoSmithKline, Collegeville, Pennsylvania, USA

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หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Tuberculin skin test and QuantiFERON®-TB Gold In-tube Test for diagnosing latent tuberculosis infection among Thai healthcare workers QuantiFERON-TB Gold In-Tube Test for Tuberculosis Prevention in HIV-Infected Patients QuanFERON®-TB GOLD in-tUBE test for diagnosing latent tuberculosis infection among clinical-year Thai medical students T‑SPOT®.TB Test for Latent Tuberculosis infection Diagnosis and Treatment Guidance in Thai Health‑Care Professionals Method verification of Isolated Chicken Eye Test QuantiFERON-TB Gold In-Tube test in active tuberculosis patients and healthy adults T-SPOT.TB test and clinical risk scoring for diagnosis of latent tuberculosis infection among Thai healthcare workers T-SPOT®.TB test and clinical risk scoring for diagnosis of latent tuberculosis infection among Thai healthcare workers. Thai Cosmetopoeia การขับเคลื่อนเศรษฐกิจสังคมไทยด้วยการสร้างสรรคุณค่าเครื่องสำอางตามเอกลักษณ์ท้องถิ่น Thai Open GLAM

คัดลอก URL

ชื่อเรื่อง (EN):	Tuberculin skin test and QuantiFERON-TB Gold In-tube Test for latent tuberculosis in Thai HIV-infected adults
ผู้แต่ง / หัวหน้าโครงการ (EN):	THANA KHAWCHAROENPORN
บทคัดย่อ (EN):	Background and objective: Limited data exist for the performance of QuantiFERON-TB Gold In-tube Test (QFT-IT) in comparison to tuberculin skin test (TST) for detecting latent tuberculosis (LTB) in patients with human immunodeficiency virus (HIV) infection from tuberculosis (TB)-endemic Asia-Pacific countries. Methods: A cohort study of Thai HIV-infected patients without history of TB or LTB treatment was conducted fromMarch 2012 through March 2013. Each patient underwent simultaneous TST and QFT-IT. Results: Among the 150 enrolled subjects, the median age was 40 years (range 17–65),53% were male, and the median CD4 count was 367 cells/_L (range 8–1290). Reactive TST and positive QFT-IT were 16% and 13%, respectively, with low concordance between tests (kappa = 0.26); correlation between TST reaction size and level of interferon-γ was moderate (r = 0.34). Independent factors associated with discordant results were long-term smoking (adjusted odds ratio (aOR) 5.74; P = 0.002) for TST-reactive, QFT-IT-negative subjects, and age greater than 52 years (aOR 5.56; P = 0.02) and female gender (aOR 4.40; P = 0.04) for TST nonreactive, QFT-IT-positive subjects. The level of agreement between both tests improved when using a TST cut-off of ≥10 mm (kappa = 0.39). Conclusions: In our setting where QFT-IT is available but has limited use due to cost, TST with a cut-off of 10 mmfor reactivity should be the initial LTB test. HIVinfected women and persons older than 52 years with non-reactive TST and long-termsmokers with reactive TST may benefit from subsequent QFT-IT.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=465
เผยแพร่โดย (EN):	1 Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathumthani 2 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand, 3 LM Mundy, GlaxoSmithKline, Collegeville, Pennsylvania, USA
คำสำคัญ (EN):	tuberculin skin test.
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science