สืบค้นงานวิจัย
Forecasting potential emergence of zoonotic diseases in South-East Asia: network analysis identifies key rodent hosts
Bordes F. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Forecasting potential emergence of zoonotic diseases in South-East Asia: network analysis identifies key rodent hosts
ผู้แต่ง / หัวหน้าโครงการ (EN): Bordes F.
บทคัดย่อ (EN): Within complex ecological systems, identifying animal species likely to play a key role in the emergence of infectious zoonotic diseases remains a major challenge. One approach consists of using information on current ecological and parasitological similarities among host species in order to predict the most likely pathways for future pathogen spillover. Using field data acquired from 15 sympatric rodent species in various habitats in Thailand, Cambodia and Laos, we built networks based on shared parasites (17 helminth and 15 microparasite species) and shared habitats among rodent species and humans. We investigated the architectures of bipartite and unipartite networks using modularity, subgroups partitioning or node centrality, to assess the relative epidemiological importance of particular rodent species. Our results showed that Rattus tanezumi, Bandicota savilei and R. exulans were consistently found to be members of subgroups that included humans in unipartite and bipartite networks on zoonotic agents and shared habitats. High values of centrality in shared zoonotic agents were found for the same three rodent species, whereas high values of shared habitats were observed for two of them. Although phylogenetically related rodent species likely shared both habitats and parasites, a lack of habitat specialization was associated with increased zoonotic parasite sharing. Our results emphasize the disproportionate importance of these three rodent species, through their high degree of connectivity with humans, which may represent a high risk for direct zoonotic spillover. Moreover, due to its high centrality in habitats, R. tanezumi may also play a key role as a bridge host. The recent discovery of new arenaviruses in rodents in South-East Asia, with associated disease in humans in Cambodia, provides an opportunity to test this empirically. The three rodent species identified using our network approach are some of the potential maintenance hosts for these new emerging arenaviruses. Synthesis and applications. Our results on rodents and their pathogens in South-East Asia show that network analysis has a high potential to improve the surveillance of emerging zoonotic pathogens by targeting key host species and potential ‘emerging’ pathogen–rodent interactions in complex and heterogeneous landscapes. © 2016 The Authors. Journal of Applied Ecology © 2016 British Ecological Society
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84996561839&doi=10.1111%2f1365-2664.12804&partnerID=40&md5=5217f5f6a613c61b8bbc899ca48ba494
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Vermes
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
หากไม่พบเอกสารฉบับเต็ม (Full Text) โปรดติดต่อหน่วยงานเจ้าของข้อมูล

การอ้างอิง

Bordes F.. "Forecasting potential emergence of zoonotic diseases in South-East Asia: network analysis identifies key rodent hosts". ไม่ระบุหน่วยงาน. ม.ป.ป.

Bordes F.. "Forecasting potential emergence of zoonotic diseases in South-East Asia: network analysis identifies key rodent hosts". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



TARR Wordcloud:
Forecasting potential emergence of zoonotic diseases in South-East Asia: network analysis identifies key rodent hosts
Bordes F.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
Progress on research on rodents and rodent-borne zoonoses in South-east Asia A traditional cattle trade network in Tak province, Thailand and its potential in the spread of infectious diseases Global parasite and Rattus rodent invasions: The consequences for rodent-borne diseases Optimization of genotyping by phenotypic analysis of clinical HIV-1 subtype CRF01_AE isolates from South-East Asia Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand Full genomic analysis of a human G9P[23] rotavirus strain from a child with diarrhea in Thailand Potential of RNAi applications to control viral diseases of farmed shrimp Emergence and Characterization of Unusual DS-1-Like G1P[8] Rotavirus Strains in Children with Diarrhea in Thailand Habitat fragmentation alters the properties of a host-parasite network: Rodents and their helminths in South-East Asia Whole-genome sequence analysis of Zika virus isolated from the plasma of an infected patient in Thailand
คัดลอก URL
กระทู้ของฉัน
ผลการสืบค้นทั้งหมด โพสต์     เรียงลำดับจาก
พัฒนาระบบโดยศูนย์ความรู้เฉพาะด้านวิศวกรรมความรู้และวิศวกรรมภาษาDeveloped by Center of Excellence for Unified Knowledge and Language Engineering
สนับสนุนโดยสำนักงานพัฒนาการวิจัยการเกษตร (องค์การมหาชน)Supported by the Agricultural Research Development Agency (Public Organization)
แบบสำรวจความพึงพอใจQuestionair