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Prevalence of ocular demodicosis among patients at Tertiary Care Center, Bangkok, Thailand
Kasetsuwan - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Prevalence of ocular demodicosis among patients at Tertiary Care Center, Bangkok, Thailand
ผู้แต่ง / หัวหน้าโครงการ (EN): Kasetsuwan
บทคัดย่อ (EN): Aim: To determine the prevalence of ocular demodicosis by both microscopic examination and molecular detection among patients at King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok. Methods: One hundred individuals were enrolled in the study and were divided into five age groups. The meibomian gland dysfunction (MGD) score and qualities of cylindrical dandruff (CD) were also determined. Demodex mite infestations of eyelash samples were screened by both microscopic examination and semi-nested polymerase chain reaction (PCR). Results: The prevalence of ocular demodicosis as determined by microscopic examination was 42% [Demodex folliculorum (D. folliculorum) 41% and Demodex brevis (D. brevis) 1%]. Among patients who had ocular Demodex infestation, 69% have CD and had an average MGD score of 4; in patients without demodicosis, 15.5% had CD and had an average MGD score of 4.12. Prevalence of ocular demodicosis as determined by semi-nested PCR was 79% (D. folliculorum 78% and D. brevis 1%). Conclusions: This is the first report on the prevalence of ocular demodicosis in Thailand. Patients with CD also had Demodex mites present. Semi-nested PCR is better than microscopy for Demodex infestation detection. An extensive survey with more representative samples is required to determine the prevalence in the country.
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ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=499
เผยแพร่โดย (EN): 1 Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 2 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand 3 Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 4 Excellence Center for Emerging Infectious Disease, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand
คำสำคัญ (EN): Demodex brevis; Demodex folliculorum; Thailand; ocular demodicosis; prevalence
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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Prevalence of ocular demodicosis among patients at Tertiary Care Center, Bangkok, Thailand
Kasetsuwan
1 Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 2 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand 3 Department of Parasitology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand 4 Excellence Center for Emerging Infectious Disease, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand
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