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Increasing incidence of hospital-acquired and healthcare-associated bacteremia in northeast Thailand: A multicenter surveillance study
Hongsuwan M. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Increasing incidence of hospital-acquired and healthcare-associated bacteremia in northeast Thailand: A multicenter surveillance study
ผู้แต่ง / หัวหน้าโครงการ (EN): Hongsuwan M.
บทคัดย่อ (EN): Little is known about the epidemiology of nosocomial bloodstream infections in public hospitals in developing countries. We evaluated trends in incidence of hospital-acquired bacteremia (HAB) and healthcare-associated bacteremia (HCAB) and associated mortality in a developing country using routinely available databases. Methods: Information from the microbiology and hospital databases of 10 provincial hospitals in northeast Thailand was linked with the national death registry for 2004-2010. Bacteremia was considered hospital-acquired if detected after the first two days of hospital admission, and healthcare-associated if detected within two days of hospital admission with a prior inpatient episode in the preceding 30 days. Results: A total of 3,424 patients out of 1,069,443 at risk developed HAB and 2,184 out of 119,286 at risk had HCAB. Of these 1,559 (45.5%) and 913 (41.8%) died within 30 days, respectively. Between 2004 and 2010, the incidence rate of HAB increased from 0.6 to 0.8 per 1,000 patient-days at risk (p<0.001), and the cumulative incidence of HCAB increased from 1.2 to 2.0 per 100 readmissions (p<0.001). The most common causes of HAB were Acinetobacter spp. (16.2%), Klebsiella pneumoniae (13.9%), and Staphylococcus aureus (13.9%), while those of HCAB were Escherichia coli (26.3%), S. aureus (14.0%), and K. pneumoniae (9.7%). There was an overall increase over time in the proportions of ESBL-producing E. coli causing HAB and HCAB. Conclusions: This study demonstrates a high and increasing incidence of HAB and HCAB in provincial hospitals in northeast Thailand, increasing proportions of ESBL-producing isolates, and very high associated mortality. © 2014 Hongsuwan et al.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84907895556&doi=10.1371%2fjournal.pone.0109324&partnerID=40&md5=1863f2d75e251a31352a04b69b022de2
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Young Adult
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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Increasing incidence of hospital-acquired and healthcare-associated bacteremia in northeast Thailand: A multicenter surveillance study
Hongsuwan M.
มหาวิทยาลัยมหิดล
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