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In silico characterization of Mx2 protein of buffalo (Bubalus bubalis) (Buffalo Bulletin,38(4))
R. Dutta - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): In silico characterization of Mx2 protein of buffalo (Bubalus bubalis) (Buffalo Bulletin,38(4))
ผู้แต่ง / หัวหน้าโครงการ (EN): R. Dutta
หน่วยงานสังกัดผู้แต่ง (EN): Assam (India). College of Veterinary Science Advanced State Biotech Hub (Assam)
บทคัดย่อ (EN): The Myxovirus resistance protein 2 of Homo sapiens is well characterized in terms of structure and function but very little is known about myxovirus resistance protein 2 (Mx2) of Bubalus bubalis. Although a few functions of buffalo Mx2 protein are known, its structural characteristics have still remained unclear. In the present study, buffalo Mx2 protein was characterized by defining its possible structure and functions using several online and offline computational tools. Besides the physico-chemical characteristics, various post translational modifications, localization, possible domains and interactions with other probable proteins were predicted using its amino acid sequence. In addition to the secondary structure, the three-dimensional structure was predicted using I-TASSER homology modelling server and a refined model was constructed in Modeller. The refined model manifested acceptable quality and stereochemistry on validation with different programs. Furthermore, a phylogenetic analysis of the protein was done and Mx2 protein of buffalo was found to have a common ancestry with that of other bovidae family members. These curated observations might provide a sound foundation for further structural and functional characterization of buffalo Mx2 protein.
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ภาษา (EN): en
เอกสารแนบ (EN): https://kukr.lib.ku.ac.th/db/kukr/search_detail/result/395221
คำสำคัญ (EN): India
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In silico characterization of Mx2 protein of buffalo (Bubalus bubalis) (Buffalo Bulletin,38(4))
R. Dutta
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Rectal prolapse in crossbred buffalo (Bubalus bubalis) calf (Buffalo Bulletin,38(1)) Characterization and validation of point mutation in MBL1 gene and its relationship with mastitis in Murrah buffalo (Bubalus bubalis) (Buffalo Bulletin,38(3)) Micrometrical observations of liver in buffalo (Bubalus bubalis) (Buffalo Bulletin,40(2)) Biometrical studies of liver in buffalo (Bubalus bubalis) (Buffalo Bulletin,39(1)) Production of buffalo milk (Bubalus bubalis) in Brazil (Buffalo Bulletin,39(3)) Histochemical studies of liver in buffalo (Bubalus bubalis) (Buffalo Bulletin,39(2)) Ovarian teratoma in a water buffalo (Bubalus bubalis) (Buffalo Bulletin (Thailand),35(4)) Gross morphological observations of liver in buffalo (Bubalus bubalis) (Buffalo Bulletin,40(1)) Molecular characterization of exon 2-3 of majorhistocompatibility complex (MHC) class I in buffalo (Bubalus bubalis) (Buffalo Bulletin (Thailand),36(3)) Milk and fatty acid composition of Anatolian water buffalo (Bubalus bubalis) from different provinces (Buffalo Bulletin,38(1))
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