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The role of evolutionary biology in research and control of liver flukes in Southeast Asia
Echaubard P. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): The role of evolutionary biology in research and control of liver flukes in Southeast Asia
ผู้แต่ง / หัวหน้าโครงการ (EN): Echaubard P.
บทคัดย่อ (EN): Stimulated largely by the availability of new technology, biomedical research at the molecular-level and chemical-based control approaches arguably dominate the field of infectious diseases. Along with this, the proximate view of disease etiology predominates to the exclusion of the ultimate, evolutionary biology-based, causation perspective. Yet, historically and up to today, research in evolutionary biology has provided much of the foundation for understanding the mechanisms underlying disease transmission dynamics, virulence, and the design of effective integrated control strategies.Here we review the state of knowledge regarding the biology of Asian liver Fluke-host relationship, parasitology, phylodynamics, drug-based interventions and liver Fluke-related cancer etiology from an evolutionary biology perspective. We consider how evolutionary principles, mechanisms and research methods could help refine our understanding of clinical disease associated with infection by Liver Flukes as well as their transmission dynamics.We identify a series of questions for an evolutionary biology research agenda for the liver Fluke that should contribute to an increased understanding of liver Fluke-associated diseases.Finally, we describe an integrative evolutionary medicine approach to liver Fluke prevention and control highlighting the need to better contextualize interventions within a broader human health and sustainable development framework. © 2016 Elsevier B.V.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84973896879&doi=10.1016%2fj.meegid.2016.05.019&partnerID=40&md5=c8527749a31ef18f3d6642c301a70b25
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Snails
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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The role of evolutionary biology in research and control of liver flukes in Southeast Asia
Echaubard P.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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