สืบค้นงานวิจัย
Proteomic and bioinformatic discovery of biomarkers for diabetic nephropathy
Thippakorn C. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Proteomic and bioinformatic discovery of biomarkers for diabetic nephropathy
ผู้แต่ง / หัวหน้าโครงการ (EN): Thippakorn C.
บทคัดย่อ (EN): Diabetes is associated with numerous metabolic and vascular risk factors that contribute to a high rate of microvascular and macro-vascular disorders leading to mortality and morbidity from diabetic complications. In this case, the major cause of death in overall diabetic patients results from diabetic nephropathy (DN) or renal failure. The risk factors and mechanisms that correspond to the development of DN are not fully understood and so far, no specific and sufficient diagnostic biomarkers are currently available other than micro- or macroalbuminuria. Therefore, this review describes current and novel protein biomarkers in the context of DN as well as probable proteins biomarkers associated with pathological processes for the early stage of DN via proteomics data together with bioinformatics. In addition, the mechanisms involved in early development of diabetic vascular disorders and complications resulting from glucose induced oxidative stress will also be explored. © 2018, Leibniz Research Centre for Working Environment and Human Factors. All rights reserved.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85046161920&doi=10.17179%2fexcli2018-1150&partnerID=40&md5=ec620c1ba19660b5ef91d6619a34f962
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Review
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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Proteomic and bioinformatic discovery of biomarkers for diabetic nephropathy
Thippakorn C.
มหาวิทยาลัยมหิดล
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