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The effects of feeding immunostimulant β-glucan on the immune response of Pangasianodon hypophthalmus
Sirimanapong W. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): The effects of feeding immunostimulant β-glucan on the immune response of Pangasianodon hypophthalmus
ผู้แต่ง / หัวหน้าโครงการ (EN): Sirimanapong W.
บทคัดย่อ (EN): Immunostimulants are food additives used by the aquaculture industry to enhance the immune response of fish, and although β-glucans are now commonly used for this purpose in aquaculture, little is known about their effects on the immune response of Pangasianodon hypophthalmus. Thus, a variety of immune parameters (e.g. phagocytosis, respiratory burst, lysozyme, complement, peroxidase, total protein, total anti-protease, total IgM, natural antibody titres, and specific IgM titres) was examined in this species after feeding fish with a basal control diet or diets supplemented with 0.05, 0.1, or 0.2g/kg fungal-derived β-glucan or 0.1% commercial yeast-derived β-glucan, as a positive control diet, for a period of four weeks. The effect of the glucans on disease resistance was then evaluated by experimentally infecting the fish with Edwardsiella ictaluri by immersion and mortalities monitored for 14 days. Samples were collected from fish for analysis at 0, 1, 3, 7, 14, 21 and 28 days post-feeding (dpf), and also at 14 days post infection (dpi). The lowest dose of fungal-derived β-glucan (0.05%) appeared insufficient to effectively stimulate the immune response of the fish, while those fed with the two highest levels of fungal-derived β-glucan had enhanced immune responses compared to the control group. Significantly elevated levels of respiratory burst activity on all days examined (. P<0.05) and lysozyme activity on 7dpf were found in the group fed 0.2% fungal-derived β-glucan, while plasma anti-protease activity was significantly enhanced (. P<0.05) by 21dpf, natural antibody titres by 3dpf and complement activity by 7dpf and also at 14dpi in the group fed 0.1% fungal-derived β-glucan. No statistical differences was seen in the level of mortalities between the dietary groups, although the group fed with the control diet had the highest level of mortalities and the groups fed with commercial yeast-derived β-glucan and 0.2% fungal-derived β-glucan the lowest. •The immune response of Pangasianodon hypophthalmus, or striped catfish, was examined.•Immunostimulant diets containing β-glucan were fed to striped catfish.•The immunostimulatory role of β-glucan on striped catfish immunity was studied.•Difference levels of β-glucan in the diets of striped catfish were evaluated.•β-glucan supplemented diet stimulated the immune response of striped catfish. © 2015 Elsevier Ltd.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-84930005177&doi=10.1016%2fj.fsi.2015.04.025&partnerID=40&md5=c345366dd51cd0ed1af8a2dd2d4e73e2
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Immunity, Innate
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
หากไม่พบเอกสารฉบับเต็ม (Full Text) โปรดติดต่อหน่วยงานเจ้าของข้อมูล

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The effects of feeding immunostimulant β-glucan on the immune response of Pangasianodon hypophthalmus
Sirimanapong W.
มหาวิทยาลัยมหิดล
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The effects of feeding β-glucan to Pangasianodon hypophthalmus on immune gene expression and resistance to Edwardsiella ictaluri Optimisation and standardisation of functional immune assays for striped catfish (Pangasianodon hypophthalmus) to compare their immune response to live and heat killed Aeromonas hydrophila as models o Immune response to recombinant Burkholderia pseudomallei FliC Concurrent infections of Flavobacterium columnare and Edwardsiella ictaluri in striped catfish, Pangasianodon hypophthalmus in Thailand Insights into the naturally acquired immune response to Plasmodium vivax malaria Francisella noatunensis subsp. orientalis infects striped catfish (Pangasianodon hypophthalmus) and common carp (Cyprinus carpio) but does not kill the hosts Naturally-acquired immune response against Plasmodium vivax rhoptry-associated membrane antigen ลักษณะของลำดับนิวคลีโอไทด์บางส่วนของยีนอินซูลินไลค์โกรทแฟคเตอร์วัน (IGF-I) ในปลาบึก (Pangasianodon gigas) และ ปลาสวาย (Pangasianodon hypophthalmus) การวิจัยและพัฒนาการเพาะเลี้ยงปลาสวาย(Pangasianodon hypophthalmus) เชิงพานิชย์ ความสัมพันธ์ทางพันธุกรรมของประชากรพ่อแม่พันธุ์ปลาสวาย (Pangasianodon hypophthalmus)
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