คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Sombat Thanprasertsuk

เผยแพร่โดย

1 Department of Disease Control, Ministry of Public Health, Thailand 2 Thailand MOPH-US CDC collaboration, Division of Global HIV and Tuberculosis, Thailand 3 Bureau of Vector Borne Diseases, Department of Disease Control, Ministry of Public Health, Thailand 4 Bureau of AIDS, TB and STIs, Department of Disease Control, Ministry of Public Health, Thailand 5 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Thailand 6 Institute of Research, Knowledge Management and Standards for Disease Control, Department of Disease Control, Ministry of Public Health, Thailand

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งานวิจัยที่แนะนำ Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand Use of dried blood spot specimens for in-house HIV drug resistance genotyping assay among infants in Thailand External Quality Assessment Scheme for HIV-1 Drug Resistance Genotyping in Thailand T‑SPOT®.TB Test for Latent Tuberculosis infection Diagnosis and Treatment Guidance in Thai Health‑Care Professionals การพัฒนาชุดตรวจและการศึกษาความชุกของการดื้อยาต้านไวรัสเอชไอวีในเด็กทารกในประเทศไทย Kit Development and Prevalence of HIV Drug Resistance in Infants in Thailand National Survey of Pretreatment HIV-Drug Resistance in Thai HIV-1-Infected Adults Spatial distribution of forensically significant blow flies in subfamily luciliinae (Diptera: Calliphoridae), Chiang Mai province, northern Thailand: Observations and modeling using GIS Four new species of begonia (begoniaceae) from Thailand Antibody response to Zika and Dengue virus among the Zika realtime PCR positive cases in Thailand, 2016

คัดลอก URL

ชื่อเรื่อง (EN):	HIV Drug Resistance among Pre-treatment Cases in Thailand: Four Rounds of Surveys during 2006-2013
ผู้แต่ง / หัวหน้าโครงการ (EN):	Sombat Thanprasertsuk
บทคัดย่อ (EN):	In Thailand, antiretroviral therapy (ART) was initiated to treat human immunodeficiency virus infection and acquired immune deficiency syndrome (HIV/AIDS) cases using the empirical regimen with no prior genotypic test to determine drug resistance. In order to assess prevalence rate of HIV drug resistance (HIVDR) among pre-treatment cases, four rounds of survey were carried out in ART clinics, including six, eight, 33 and four ART clinics in each round during 2006-2013. For which, HIVDR testing results were available in 310, 350, 797, and 413 cases in four rounds. It was revealed that HIVDR rates among naive cases were 2.0%, 2.8%, 4.0% and 4.8%, while in experienced cases, the rates were 0, 3.3%, 11.4% and 13.9%. The rates among all cases were 1.9%, 2.9%, 4.4% and 5.6%. Resistant drugs with the highest rates among all cases in the survey round 4 were nevirapine (3.6%) and efavirenz (3.1%). The results indicated the need to continue surveillance for pre-treatment HIVDR, and posed challenges to implement activities for protecting efficacy and prolong the use of empirical first-line regimen. A strategy to apply genotyping test, in a cost-effective approach, should be considered to prepare for situation when HIVDR increases beyond a critical level.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=534
เผยแพร่โดย (EN):	1 Department of Disease Control, Ministry of Public Health, Thailand 2 Thailand MOPH-US CDC collaboration, Division of Global HIV and Tuberculosis, Thailand 3 Bureau of Vector Borne Diseases, Department of Disease Control, Ministry of Public Health, Thailand 4 Bureau of AIDS, TB and STIs, Department of Disease Control, Ministry of Public Health, Thailand 5 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Thailand 6 Institute of Research, Knowledge Management and Standards for Disease Control, Department of Disease Control, Ministry of Public Health, Thailand
คำสำคัญ (EN):	antiretroviral therapy; HIV; resistance; pre-treatment; Thailand
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science