คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Suwadee Jirasakpisarn

เผยแพร่โดย

1 Department of Pediatrics, Pranangklao Hospital, Nonthaburi Province 2 National Institute of Health of Thailand, Department of Medical Sciences, Nonthaburi Province

เผยแพร่เมื่อ ไม่ระบุวันที่เผยแพร่

หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Zika Incidence among Patients with Suspected Dengue Fever (Preliminary Report) Interferon lambda 1 is associated with dengue severity in Thailand Effectiveness of BOX-PCR in Differentiating Genetic Relatedness among Salmonella enterica Serotype 4,[5],12:i:- Isolates from Hospitalized Patients and Minced Pork Samples in Northern Thailand Management and outcomes of severe dengue patients presenting with sepsis in a tropical country Potent neutralizing human monoclonal antibodies preferentially target mature dengue virus particles: Implication for novel strategy for dengue vaccine Clinical epidemiology and outcomes of community acquired infection and sepsis among hospitalized patients in a resource limited setting in Northeast Thailand: A prospective observational study (Ubon-s Characterization of human CD8 T cell responses in dengue virus-infected patients from India Prevalence of ocular demodicosis among patients at Tertiary Care Center, Bangkok, Thailand Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection Low levels of antibody-dependent enhancement in vitro using viruses and plasma from dengue patients

คัดลอก URL

ชื่อเรื่อง (EN):	Dengue serotype and clinical severity among pediatric patients : a decade review
ผู้แต่ง / หัวหน้าโครงการ (EN):	Suwadee Jirasakpisarn
บทคัดย่อ (EN):	Background: Dengue is the major problem of public health in Thailand leading to abundantly fatal cases. Now vaccine is available whereas low efficacy against serotype-2 and valuable in seropositive individuals, whilst lack of practical testing. Objectives: To review of dengue in children about prevalence, demographic data, diagnosis, serotype and its collelation including primary/secondary infection classified by age group; apply data in clinical use of dengue vaccine. Materials and Methods: Retrospectively reviewed all patients <15 year-old who were serologically confirmed dengue infection at Pranangklao hospital during 1 July 2005-31 December 2015. Results: There were 1,336 cases per reviewd (female 50.8%). The mean age was 9.6±3.3 year (min-max; 0.1-14.8 year); 1,031 cases had clinical diagnosis: DF (30.4%), DHF (66.2%), DSS (3.4%). 861 cases who were clearly classified of infection (primary infection 139 cases and secondary infection 722 cases); 465 cases (54%) in age group >10-15 years were primary infection 66 cases and secondary infection 399 cases. 810 cases who were identifed virus by RT-PCR and/or viral isolation; DENV-1 was predominant serotype (51.5%) followed by DENV-3 (23.1%), DENV-2 (18.7%) and DENV-4 (6.3%) respectively. Mainly serotypes of DHF/DSS were DENV-2 in primary infection and DENV-1 in secondary infection. Conclusion: Dengue is move forward to affect early adolescence, more than 50% of dengue-experienced cases are around 10-15 year-old furthermore largely causative by serotype-1. Severe dengue depend on multifactor. Hopefully, this data help to consider dengue vaccination among Thai children.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=647
เผยแพร่โดย (EN):	1 Department of Pediatrics, Pranangklao Hospital, Nonthaburi Province 2 National Institute of Health of Thailand, Department of Medical Sciences, Nonthaburi Province
คำสำคัญ (EN):	decade review
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science