สืบค้นงานวิจัย
Exploring the salivary microbiome of children stratified by the oral hygiene index
Mashima I. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Exploring the salivary microbiome of children stratified by the oral hygiene index
ผู้แต่ง / หัวหน้าโครงการ (EN): Mashima I.
บทคัดย่อ (EN): Poor oral hygiene often leads to chronic diseases such as periodontitis and dental caries resulting in substantial economic costs and diminished quality of life in not only adults but also in children. In this study, the salivary microbiome was characterized in a group of children stratified by the Simplified Oral Hygiene Index (OHI-S). Illumina MiSeq high-throughput sequencing based on the 16S rRNA was utilized to analyze 90 salivary samples (24 Good, 31 Moderate and 35 Poor oral hygiene) from a cohort of Thai children. A total of 38,521 OTUs (Operational Taxonomic Units) with a 97% similarity were characterized in all of the salivary samples. Twenty taxonomic groups (Seventeen genera, two families and one class; Streptococcus, Veillonella, Gemellaceae, Prevotella, Rothia, Porphyromonas, Granulicatella, Actinomyces, TM-7-3, Lepto-trichia, Haemophilus, Selenomonas, Neisseria, Megasphaera, Capnocytophaga, Oribacterium, Abiotrophia, Lachnospiraceae, Peptostreptococcus, and Atopobium) were found in all subjects and constituted 94.5–96.5% of the microbiome. Of these twenty genera, the proportion of Streptococcus decreased while Veillonella increased with poor oral hygiene status (P < 0.05). Furthermore, an unassigned species of Veillonella, Veillonella dispar and Veillonella parvula tended to be elevated in the Poor oral hygiene group. This is the first study demonstrating an important association between increase of Veillonella and poor oral hygiene status in children. However, further studies are required to identify the majority of Veillonella at species level in salivary microbiome of the Poor oral hygiene group. © 2017 Mashima et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85029838421&doi=10.1371%2fjournal.pone.0185274&partnerID=40&md5=8a9087fe742eede85b9b284bc4a9de8f
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Saliva
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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การอ้างอิง

Mashima I.. "Exploring the salivary microbiome of children stratified by the oral hygiene index". ไม่ระบุหน่วยงาน. ม.ป.ป.

Mashima I.. "Exploring the salivary microbiome of children stratified by the oral hygiene index". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Exploring the salivary microbiome of children stratified by the oral hygiene index
Mashima I.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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