คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Waralee Aksornchindarat

เผยแพร่โดย

1 Faculty of Medicine, Thammasat University, Pathumthani, Thailand. 2 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand. 3 Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.

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งานวิจัยที่แนะนำ T-SPOT®.TB test and clinical risk scoring for diagnosis of latent tuberculosis infection among Thai healthcare workers. Tuberculin skin test and QuantiFERON®-TB Gold In-tube Test for diagnosing latent tuberculosis infection among Thai healthcare workers T‑SPOT®.TB Test for Latent Tuberculosis infection Diagnosis and Treatment Guidance in Thai Health‑Care Professionals QuanFERON®-TB GOLD in-tUBE test for diagnosing latent tuberculosis infection among clinical-year Thai medical students Tuberculin skin test and QuantiFERON-TB Gold In-tube Test for latent tuberculosis in Thai HIV-infected adults Thai Cosmetopoeia การขับเคลื่อนเศรษฐกิจสังคมไทยด้วยการสร้างสรรคุณค่าเครื่องสำอางตามเอกลักษณ์ท้องถิ่น Thai Open GLAM T-SPOT.TB test ในการตรวจวินิจฉัยการติดเชื้อวัณโรคและติดตามการรักษาแบบป้องกันในกลุ่มบุคลากรทางการแพทย์ T-SPOT.TB test for detecting Mycobacterium tuberculosis infection and monitoring the prophylactic QuantiFERON-TB Gold In-Tube Test for Tuberculosis Prevention in HIV-Infected Patients ปัจจัยเสี่ยงและอัตราการติดเชื้อวัณโรคแบบแฝงในกลุ่มบุคลากรทางการแพทย์ Risk factors and prevalence for latent tuberculosis infection among healthcare workers

คัดลอก URL

ชื่อเรื่อง (EN):	T-SPOT.TB test and clinical risk scoring for diagnosis of latent tuberculosis infection among Thai healthcare workers
ผู้แต่ง / หัวหน้าโครงการ (EN):	Waralee Aksornchindarat
บทคัดย่อ (EN):	Background: Screening for latent tuberculosis infection (LTBI) is important to identify healthcare workers (HCWs) benefiting from preventive therapy. Interferon-gamma release assays (IGRAs) are sensitive and specific tests for LTBI diagnosis. However, in settings where IGRAs are not available, clinical risk assessment may be used as an alternative to diagnose LTBI. Methods: A cross-sectional study was conducted among HCWs of a tertiary-care university hospital in Thailand. All HCWs underwent T-SPOT_.TB test (T-SPOT) and assessment of LTBI clinical risks. Clinical risks associated with T-SPOT positivity were determined by multivariable logistic regression analysis and were given scores accordingly. The performance of the clinical risk scoring was evaluated in comparison to T-SPOT. Results: Among 140 enrolled HCWs, 125 (89%) were females, the median age was 27 years and 23 (16%) had T-SPOT positivity. Independent factors associated with T-SPOT positivity were age _30 years (adjusted odds ratio [aOR] 3.95; P = 0.002), working duration _60 months (aOR 3.75, P = 0.004) and frequency of TB contact _6 times (aOR 8.83, P = 0.005). The study’s clinical risk scoring had the area under the curve by receiver operating curve analysis of 0.76 (P < 0.001) using T-SPOT positivity as a reference standard. The score of _3 had the best performance in diagnosing LTBI with sensitivity, specificity, positive predictive value and negative predictive value of 70%, 71%, 32% and 92%, respectively.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=556
เผยแพร่โดย (EN):	1 Faculty of Medicine, Thammasat University, Pathumthani, Thailand. 2 National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand. 3 Division of Infectious Diseases, Faculty of Medicine, Thammasat University, Pathumthani, Thailand.
คำสำคัญ (EN):	Latent tuberculosis infection; Healthcare workers; T-SPOT_.TB; Clinical risk scoring; Thailand
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science