คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Napa Onvimala

เผยแพร่โดย

1 Department of Microbiology and immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. 2 Department of Medical Sciences,National Institute of Health, Ministry of Public Health, Nonthaburi, Thailand. 3 Department of Disease, Bureau of General Communicable Disease, MOPH, Nonthaburi, Thailand.

เผยแพร่เมื่อ ไม่ระบุวันที่เผยแพร่

หน่วยงาน ไม่ระบุหน่วยงาน

งานวิจัยที่แนะนำ Group B Streptococcal bacteremia burden and trends over time, 2007-15, Thailand Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand Wolbachia supergroups A and B in natural populations of medically important filth flies (Diptera : Muscidae, Calliphoridae, and Sarcophagidae) in Thailand Prevalence of zoonotic Bartonella species among rodents and shrews in Thailand Draft Genome Sequence of a Clostridium botulinum Isolate from Thailand Harboring the Subtype bont/B8 Gene Circulation of HIV-1 Multiple Complexity Recombinant Forms Among Female Sex Workers Recently Infected with HIV-1 in Thailand Mangrove forests in Thailand Progress on Rubber Breeding of Thailand Molecular Characterization of Clostridium botulinum Isolates from Foodborne Outbreaks in Thailand, 2010 Emergence and Characterization of Unusual DS-1-Like G1P[8] Rotavirus Strains in Children with Diarrhea in Thailand

คัดลอก URL

ชื่อเรื่อง (EN):	Genotyping of non-polio enteroviruses associated with acute flaccid paralysis in Thailand in 2013 and 2014
ผู้แต่ง / หัวหน้าโครงการ (EN):	Napa Onvimala
บทคัดย่อ (EN):	Background: Acute ﬂaccid paralysis (AFP) surveillance was conducted as part of the World Health Organization’s strategy for completely eradicating poliomyelitis and leaving non-polio enteroviruses NPEVs as one of the main potential causes of AFP. We aimed to detect NPEV in association with AFP. Methods: We used 459 isolates reported to be Negative Polio and some NPEVs by the World Health Organization Polio Regional Reference Laboratory (Thailand), which had been obtained during polio surveillance programs conducted in Thailand in 2013–2014. Of 459 isolates, 35 belonged to the genus Enterovirus by RT-PCR and genotyping by DNA sequencing. Results: This study found 17 NPEV genotypes, with 3, 13 and 1 belonging to enterovirus (EV) species A (EV-A), EV-B, and EV-C, respectively. The EV-A types identiﬁed included coxsackievirus A2 (CA2), CA4, and EV71, typically associated with hand, foot and mouth diseases. EV-B is the most prevalent cause of AFP in Thailand, while CA21 was the only type of EV-C detected. The EV-B species (13/35; 76.5%) constituted the largest proportion of isolates, followed by EV-A (3/35; 17.6%) and EV-C (1/35; 5.9%). For the EV-B species, Echovirus (E) 30 and CVB were the most frequent isolates. E30, CVB, E14, and E6 were considered endemic strains. Conclusion: NPEVs, e.g. CA4, are reported for the ﬁrst time in Thailand. Despite some limitations to this study, this is the ﬁrst report on the circulation patterns of NPEVs associated with AFP in Thailand. AFP surveillance has unearthed many unknown NPEVs and, the cases of death due to AFP occur annually. Therefore, it is important to study NPEVs in the wake of the eradication of poliovirus in the context of the continued incidence of paralysis.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=758
เผยแพร่โดย (EN):	1 Department of Microbiology and immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand. 2 Department of Medical Sciences,National Institute of Health, Ministry of Public Health, Nonthaburi, Thailand. 3 Department of Disease, Bureau of General Communicable Disease, MOPH, Nonthaburi, Thailand.
คำสำคัญ (EN):	Coxsackievirus (CA)
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science