สืบค้นงานวิจัย
Potential of RNAi applications to control viral diseases of farmed shrimp
Itsathitphaisarn O. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Potential of RNAi applications to control viral diseases of farmed shrimp
ผู้แต่ง / หัวหน้าโครงการ (EN): Itsathitphaisarn O.
บทคัดย่อ (EN): Viral pathogens pose a primary threat to global shrimp aquaculture. Despite the urgent industry need for them, practical anti-viral control methods are unavailable due, in part, to lack of an adaptive immune response in crustaceans that renders conventional vaccination methods ineffective. One currently studied method of high interest for protecting shrimp against viral infection relies on the post-transcriptional gene silencing mechanism called RNA interference (RNAi) that is induced by gene-specific constructs of double stranded RNA (dsRNA). Although this approach was first described for successful protection of shrimp against white spot disease (WSD) by injecting dsRNA specific to genes of white spot syndrome virus (WSSV) into shrimp in the laboratory in 2005 no practical method for use of dsRNA in shrimp farms has been developed to date. The apparent bottleneck for farm-scale applications of RNAi-mediated viral control in shrimp aquaculture is the lack of simple and cost-effective delivery methods. This review summarizes recent studies on use and delivery of dsRNA to shrimp via injection and oral routes in hatcheries and on farms and it discusses the research directions that might lead to development of practical methods for applications with farmed shrimp. Oral delivery methods tested so far include use of dsRNA-expressing bacteria as a component of dry feed pellets or use of living brine shrimp (Artemia) pre-fed with dsRNA before they are fed to shrimp. Also tested have been dsRNA enclosed in nanocontainers including chitosan, liposomes and viral-like particles (VLP) before direct injection or use as components of feed pellets for hatchery or pond-reared shrimp. © 2016 Elsevier Inc.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85008144250&doi=10.1016%2fj.jip.2016.11.006&partnerID=40&md5=e076902f9ed87cef850889d3ea3b80f2
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Virus Diseases
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
หากไม่พบเอกสารฉบับเต็ม (Full Text) โปรดติดต่อหน่วยงานเจ้าของข้อมูล

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Itsathitphaisarn O.. "Potential of RNAi applications to control viral diseases of farmed shrimp". ไม่ระบุหน่วยงาน. ม.ป.ป.

Itsathitphaisarn O.. "Potential of RNAi applications to control viral diseases of farmed shrimp". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Potential of RNAi applications to control viral diseases of farmed shrimp
Itsathitphaisarn O.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
A future vision for disease control in shrimp aquaculture Probiotic bacteria (Lactobacillus plantarum) expressing specific double-stranded RNA and its potential for controlling shrimp viral and bacterial diseases Applications of microalgal biotechnology for disease control in aquaculture DISEASES OF RUBBER (Hevea brasiliensis) IN THE PHILIPPINES, CONTROL AND SCREENING FOR RESISTANCE Shrimp hemocyte homeostasis-associated protein (PmHHAP) interacts with WSSV134 to control apoptosis in white spot syndrome virus infection Effect of urea-extracted sericin on melanogenesis: Potential applications in post-inflammatory hyperpigmentation Genomics Assisted Crop Improvement – Applications and Potential in Tree Improvement A traditional cattle trade network in Tak province, Thailand and its potential in the spread of infectious diseases Research Progresses in Monitoring and Control of Several Diseases and Pests Attacking Rubber Trees in China Facts, truths and myths about SPF shrimp in Aquaculture
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