คลังข้อมูลการวิจัยการเกษตรไทย

ผู้แต่ง Saori Fukuda

เผยแพร่โดย

1 Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan 2 National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand 3 Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan 4 Center for Research Promotion and Support, Joint Research Support Promotion Facility, Fujita Health University, Toyoake, Aichi, Japan 5 Bhumibol Adulyadej Hospital, Bangkok, Thailand 6 Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Nonthaburi, Thailand 7 Osaka Institute of Public Health, Osaka, Japan

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งานวิจัยที่แนะนำ Full Genome Characterization of Novel DS-1-Like G8P[8] Rotavirus Strains that Have Emerged in Thailand: Reassortment of Bovine and Human Rotavirus Gene Segments in Emerging DS-1-Like Intergenogroup Re Emergence and Characterization of Unusual DS-1-Like G1P[8] Rotavirus Strains in Children with Diarrhea in Thailand Full genome-based characterization of G4P[6] rotavirus strains from diarrheic patients in Thailand: Evidence for independent porcine-to-human interspecies transmission events Full genomic analysis of a human G9P[23] rotavirus strain from a child with diarrhea in Thailand High prevalence of G3P[8] rotavirus strains with a short electropherotype in acute gastroenteritis cases in Thailand High prevalence of equine‐like G3P[8] rotavirus in children and adults with acute gastroenteritis in Thailand Rotavirus outbreak in adults, Thailand 2018 Molecular detection and characterization of noroviruses in river water in Thailand Molecular Characterization of Clostridium botulinum Isolates from Foodborne Outbreaks in Thailand, 2010 Evaluating the first introduction of rotavirus vaccine in Thailand : Moving from evidence to policy

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ชื่อเรื่อง (EN):	Full genome characterization of novel DS-1-like G9P[8] rotavirus strains that have emerged in Thailand
ผู้แต่ง / หัวหน้าโครงการ (EN):	Saori Fukuda
บทคัดย่อ (EN):	The emergence and rapid spread of unusual DS-1-like intergenogroup reassortant rotaviruses having G1/3/8 genotypes have been recently reported from major parts of the world (Africa, Asia, Australia, Europe, and the Americas). During rotavirus surveillance in Thailand, three novel intergenogroup reassortant strains possessing the G9P[8] genotype (DBM2017-016, DBM2017-203, and DBM2018-291) were identified in three stool specimens from diarrheic children. In the present study, we determined and analyzed the full genomes of these three strains. On full-genomic analysis, all three strains were found to share a unique genotype constellation comprising both genogroup 1 and 2 genes: G9-P[8]-I2-R2-C2-M2-A2-N2-T2-E2-H2. Phylogenetic analysis demonstrated that each of the 11 genes of the three strains was closely related to that of emerging DS-1-like intergenogroup reassortant, human, and/or locally circulating human strains. Thus, the three strains were suggested to be multiple reassortants that had acquired the G9-VP7 genes from co-circulating Wa-like G9P[8] rotaviruses in the genetic background of DS-1-like intergenogroup reassortant (likely equine-like G3P[8]) strains. To our knowledge, this is the first description of emerging DS-1-like intergenogroup reassortant strains having the G9P[8] genotype. Our observations will add to the growing insights into the dynamic evolution of emerging DS-1-like intergenogroup reassortant rotaviruses through reassortment.
บทคัดย่อ:	ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN):	en
เอกสารแนบ (EN):	http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=567
เผยแพร่โดย (EN):	1 Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi, Japan 2 National Institute of Health, Department of Medical Sciences, Nonthaburi, Thailand 3 Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi, Japan 4 Center for Research Promotion and Support, Joint Research Support Promotion Facility, Fujita Health University, Toyoake, Aichi, Japan 5 Bhumibol Adulyadej Hospital, Bangkok, Thailand 6 Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Nonthaburi, Thailand 7 Osaka Institute of Public Health, Osaka, Japan
คำสำคัญ (EN):	Thailand
เจ้าของลิขสิทธิ์ (EN):	National Institute of Health, Department of Medical Science