สืบค้นงานวิจัย
Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study
Leopold S.J. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study
ผู้แต่ง / หัวหน้าโครงการ (EN): Leopold S.J.
บทคัดย่อ (EN): Introduction Patients with severe malaria or sepsis are at risk of developing life-threatening acute respiratory distress syndrome (ARDS). The objective of this study was to evaluate point-of-care lung ultrasound as a novel tool to determine the prevalence and early signs of ARDS in a resource-limited setting among patients with severe malaria or sepsis. Materials and methods Serial point-of-care lung ultrasound studies were performed on four consecutive days in a planned sub study of an observational cohort of patients with malaria or sepsis in Bangladesh. We quantified aeration patterns across 12 lung regions. ARDS was defined according to the Kigali Modification of the Berlin Definition. Results Of 102 patients enrolled, 71 had sepsis and 31 had malaria. Normal lung ultrasound findings were observed in 44 patients on enrolment and associated with 7% case fatality. ARDS was detected in 10 patients on enrolment and associated with 90% case fatality. All patients with ARDS had sepsis, 4 had underlying pneumonia. Two patients developing ARDS during hospitalisation already had reduced aeration patterns on enrolment. The SpO 2 /FiO 2 ratio combined with the number of regions with reduced aeration was a strong prognosticator for mortality in patients with sepsis (AUROC 91.5% (95% Confidence Interval: 84.6%-98.4%)). Conclusions This study demonstrates the potential usefulness of point-of-care lung ultrasound to detect lung abnormalities in patients with malaria or sepsis in a resource-constrained hospital setting. LUS was highly feasible and allowed to accurately identify patients at risk of death in a resource limited setting. © 2018 Leopold et al.This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85058396673&doi=10.1371%2fjournal.pone.0204832&partnerID=40&md5=0f31d6d6a532bc7a12e45c9a3b4d7d4b
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Ultrasonography
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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Leopold S.J.. "Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study". ไม่ระบุหน่วยงาน. ม.ป.ป.

Leopold S.J.. "Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Point-of-care lung ultrasound for the detection of pulmonary manifestations of malaria and sepsis: An observational study
Leopold S.J.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
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