สืบค้นงานวิจัย
First study of topical selamectin efficacy for treating cats naturally infected with Brugia malayi and Brugia pahangi under field conditions
Sarasombath P.T. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): First study of topical selamectin efficacy for treating cats naturally infected with Brugia malayi and Brugia pahangi under field conditions
ผู้แต่ง / หัวหน้าโครงการ (EN): Sarasombath P.T.
บทคัดย่อ (EN): Lymphatic filariae are important human and animal parasites. Infection by these parasites could lead to severe morbidity and has significant socioeconomic impacts. Topical selamectin is a semi-synthetic macrocyclic lactone that is widely used to prevent heartworm infection. Up until now, there were no studies that investigated the efficacy of selamectin in lymphatic filariae. Therefore, we aimed to study the chemotherapeutic and chemoprophylactic efficacies of selamectin use for cats in brugian filariasis-endemic areas in Southern Thailand. To assess chemotherapeutic efficacy of topical selamectin, eight Brugia malayi and six Brugia pahangi microfilaremic cats were treated with a single administration of topical selamectin. For chemoprophylactic efficacy assessment, a single application of topical selamectin was administrated to 9 healthy, uninfected cats. The cats in both groups were subjected to a monthly blood testing for microfilariae and filarial DNA for 1 year. Topical selamectin treatment in B. malayi and B. pahangi microfilaremic cats showed 100% effectivity in eradicating microfilaremia but only 78.5% effectivity in eliminating filarial DNA. In the chemoprophylactic group, selamectin demonstrated 66.7% efficacy in preventing B. malayi infection. Our findings suggest that a single administration of 6 mg/kg topical selamectin given every two months could effectively prevent B. malayi infection. Application of topical selamectin twice a year could block circulating microfilariae. Since there are no treatment guidelines currently available for lymphatic filarial infection in cats, the data obtained from this study could be used to guide the management of brugian lymphatic filarial infection in reservoir cats. © 2019, Springer-Verlag GmbH Germany, part of Springer Nature.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85061397730&doi=10.1007%2fs00436-019-06248-3&partnerID=40&md5=94657d8f22aca8a9a00b41163d8c60fb
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Thailand
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
หากไม่พบเอกสารฉบับเต็ม (Full Text) โปรดติดต่อหน่วยงานเจ้าของข้อมูล

การอ้างอิง

Sarasombath P.T.. "First study of topical selamectin efficacy for treating cats naturally infected with Brugia malayi and Brugia pahangi under field conditions". ไม่ระบุหน่วยงาน. ม.ป.ป.

Sarasombath P.T.. "First study of topical selamectin efficacy for treating cats naturally infected with Brugia malayi and Brugia pahangi under field conditions". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



TARR Wordcloud:
First study of topical selamectin efficacy for treating cats naturally infected with Brugia malayi and Brugia pahangi under field conditions
Sarasombath P.T.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
Therpeutic efficacy evaluation of commonly used antitrypanosomal drugs in naturally infected buffaloes (Buffalo Bulletin,40(1)) VARIATIONS IN THE CHARACTERISTICS OF PASTURE LEGUME ECOTYPES UNDER AND OPEN FIELD CONDITIONS Efficacy of modified co-synch plus protocol with or without progesterone device for estrus induction and conception rate in Murrah buffaloes under field conditions during summer season (Buffalo Bullet Evidence of vertical transmission and tissue tropism of Streptococcosis from naturally infected red tilapia (Oreochromis spp.) Effect of Stake Priming with Nutrient Solution on Growth and Yield of Cassava Grown under Greenhouse and Field Conditions MAGNETIC FIELD LINE RANDOM WALK in ISOTROPIC TURBULENCE with VARYING MEAN FIELD Efficacy and safety of topical Trikatu preparation in, relieving mosquito bite reactions : A randomized controlled trial Magnetic field line random walk in isotropic turbulence with zero mean field Efficacy and safety of oral antidiabetic drugs in comparison to insulin in treating gestational diabetes mellitus: A meta-analysis Vertical transmission and concurrent infection of multiple bacterial pathogens in naturally infected red tilapia (Oreochromis spp.)
คัดลอก URL
กระทู้ของฉัน
ผลการสืบค้นทั้งหมด โพสต์     เรียงลำดับจาก
พัฒนาระบบโดยศูนย์ความรู้เฉพาะด้านวิศวกรรมความรู้และวิศวกรรมภาษาDeveloped by Center of Excellence for Unified Knowledge and Language Engineering
สนับสนุนโดยสำนักงานพัฒนาการวิจัยการเกษตร (องค์การมหาชน)Supported by the Agricultural Research Development Agency (Public Organization)
แบบสำรวจความพึงพอใจQuestionair