สืบค้นงานวิจัย
Association of antioxidant status and inflammatory markers with metabolic syndrome in Thais
Suriyaprom K. - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Association of antioxidant status and inflammatory markers with metabolic syndrome in Thais
ผู้แต่ง / หัวหน้าโครงการ (EN): Suriyaprom K.
บทคัดย่อ (EN): An oxidant/antioxidant disequilibrium has been suggested as having a role in the pathogenesis of some diseases. Metabolic syndrome (MS) is significantly associated with cardiovascular disease and type 2 diabetes. The pathogenesis of MS is complex and not well understood. The purposes of the present study were to compare enzymatic and non-enzyme antioxidants, anthropometric, hematological, and biochemical findings between subjects with MS and without MS and to evaluate the relationship between antioxidant status and hematological parameters with the components of MS. Methods: Metabolic syndrome was assessed by using the modified National Cholesterol Education Program, Adult Treatment Panel III criteria. Three hundred Thais, 124 with MS and 176 without MS, were included in the study. Each subject was tested for erythrocyte superoxide dismutase (SOD), glutathione peroxidase, (GPX), catalase (CAT), albumin and vitamin C levels, and hematological findings. Results: Subjects with MS had lower SOD and CAT levels than those without MS (p < 0.01). Subjects with MS had lower vitamin C and albumin levels than those without MS (p < 0.05). The hematological findings were not significantly different between those with and without MS except the white blood cell (WBC) count which was significantly higher in those with MS. SOD and CAT levels were significantly positively associated with HDL-C levels and negatively associated with components of MS. After adjusting for potential covariates, we found lower SOD and vitamin C levels and higher WBC counts were significantly associated with MS (p < 0.05). Conclusions: These findings suggest an alteration in antioxidant status and an increase in inflammatory markers are associated with MS and its components among Thais; subjects with MS may be more likely to have oxidative stress problems. © 2019 The Author(s).
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://www.scopus.com/inward/record.uri?eid=2-s2.0-85059495082&doi=10.1186%2fs41043-018-0158-9&partnerID=40&md5=13377a594fd094851302eae3973b44e7
เผยแพร่โดย (EN): มหาวิทยาลัยมหิดล
คำสำคัญ (EN): Thai
เจ้าของลิขสิทธิ์ (EN): มหาวิทยาลัยมหิดล
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Suriyaprom K.. "Association of antioxidant status and inflammatory markers with metabolic syndrome in Thais". ไม่ระบุหน่วยงาน. ม.ป.ป.

Suriyaprom K.. "Association of antioxidant status and inflammatory markers with metabolic syndrome in Thais". ไม่ระบุหน่วยงาน. ม.ป.ป.. Print.



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Association of antioxidant status and inflammatory markers with metabolic syndrome in Thais
Suriyaprom K.
มหาวิทยาลัยมหิดล
ไม่ระบุวันที่เผยแพร่
Association between haplotype tagging single nucleotide polymorphisms of the ret proto-oncogene (RET) and hirschsprung disease in thais Dietary Pattern and Metabolic Syndrome in Thai Adults Data mining for the identification of metabolic syndrome status Association of IL1B –31C/T and IL1RA Variable Number of an 86-bp Tandem Repeat With Dengue Shock Syndrome in Thailand Antioxidant and antibacterial potentials of some Thai native plant extracts Nutrient Status of Soils and Leaves of Immature Rubber in the East Coast of Upper Part of Southern Thailand Development of ultra-short PCR assay to reveal BRAF V600 mutation status in Thai colorectal cancer tissues Association between waist circumference at two measurement sites and indicators of metabolic syndrome and cardiovascular disease among Thai adults Inverse association of plasma IgG antibody to Aggregatibacter actinomycetemcomitans and high C-reactive protein levels in patients with metabolic syndrome and periodontitis Predicting metabolic syndrome using the random forest method
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