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Melanocortin 1 receptor (MC1R) gene polymorphism and its association with coat colour patterns in Nagpuri and Purnathadi buffaloes (Buffalo Bulletin,41(3))
Shyam Ganesh Deshmukh - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Melanocortin 1 receptor (MC1R) gene polymorphism and its association with coat colour patterns in Nagpuri and Purnathadi buffaloes (Buffalo Bulletin,41(3))
ผู้แต่ง / หัวหน้าโครงการ (EN): Shyam Ganesh Deshmukh
หน่วยงานสังกัดผู้แต่ง (EN): Maharashtra (India). Department of Animal Genetics and Breeding
บทคัดย่อ (EN): Melanin is the pigment of skin (coat) and hairs in all mammals. The 954 bp long MC1R gene codes for the production of MC1R or the alpha-MSH receptors which are present on the melanosomes. These receptors regulate the synthesis of melanin pigments viz., eumelanin or phaeomelanin leading to black and reddish to yellowish pigmentations respectively. PCR-RFLP analysis of 138 bp region of MC1R gene was conducted in two buffalo populations having distinct coat colours, Nagpuri (black) and Purnathadi (whitish). Three genotypes, E**(D) ED, E**(D)E* and E*E* were observed at frequencies of 0.86, 0.03 and 0.11 for Nagpuri and 0.74, 0.08 and 0.18 in Purnathadi buffaloes, similarly the observed gene frequencies for ED and E* alleles were 0.87, 0.13 and 0.78, 0.22 in Nagpuri and Purnathadi buffaloes, respectively. DNA-sequencing revealed a transition mutation (AG) at 118 bp locus confirming polymorphism, however presence in both the population failed to point towards any specific role in body coat colour of buffaloes.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): https://kukr.lib.ku.ac.th/db/kukr/search_detail/result/419635
คำสำคัญ (EN): Purnathadi
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Melanocortin 1 receptor (MC1R) gene polymorphism and its association with coat colour patterns in Nagpuri and Purnathadi buffaloes (Buffalo Bulletin,41(3))
Shyam Ganesh Deshmukh
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Association of Melatonin receptor 1A (MTNR1A) gene polymorphism with seasonal suppression of fertility in buffaloes (Buffalo Bulletin,41(4)) Expression and structural variations of toll-like receptor 4 gene in buffalo and cattle (Buffalo Bulletin,41(1)) Effect of season and stage of lactation on milk components in Purnathadi buffaloes (Buffalo Bulletin,41(3)) Molecular characterization of buffalo alpha s1-casein gene (Buffalo Bulletin,41(3)) Incidence of various haemoprotozoan diseases in buffaloes (Buffalo Bulletin,41(3)) Ultrasonography and biochemical studies of hepatobiliary system in buffaloes (Buffalo Bulletin,41(2)) Clinico-biochemical and therapeutic management of mammitis in buffaloes (Buffalo Bulletin,41(2)) Efficacy of antioxidant in the therapy of subclinical mastitis in buffaloes (Buffalo Bulletin,41(1)) Diagnosis and therapeutic management of oral tumours in Murrah buffaloes (Buffalo Bulletin,41(1)) Aquatic fern Azolla affecting milk production in buffaloes (Buffalo Bulletin,41(4))
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