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Pertussis surveillance in a children hospital in Bangkok, Thailand
Piyarat Suntarattiwong - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Pertussis surveillance in a children hospital in Bangkok, Thailand
ผู้แต่ง / หัวหน้าโครงการ (EN): Piyarat Suntarattiwong
บทคัดย่อ (EN): OBJECTIVES: To investigate the incidence, clinical characteristics and cost associated with pertussis in Thai children with persistent cough. METHODS: A prospective study was conducted among children aged 0-18 years with persistent cough for ≥7days with at least one of the following: paroxysm, inspiratory whooping, or post-tussive emesis. Nasopharyngeal swabs were obtained and tested for pertussis real time polymerase chain reaction (RT-PCR). RESULTS: 19.6% of children (28 out of 143) had pertussis confirmed by RT-PCR, 75% of cases occurred in children who were too young to complete their primary series of vaccine. Paroxysm and post-tussive emesis were the most consistent clinical features, identified in 96% and 93% of cases, respectively, whooping was found in only 18%. Pertussis cases were more likely to have household cough contact (64% versus 30%, p<0.001), be hospitalized (79% versus 58%, p=0.048) and experience protracted duration of cough (47 vs. 20 days, p<0.001) compare to their counterpart. CONCLUSION: Pertussis in Thai children is not infrequent and the common age group is young infant before completion of primary series of pertussis vaccine at six months of age, underline the importance of maternal pertussis immunization.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=541
เผยแพร่โดย (EN): 1 Queen Sirikit National Institute of Child Health, Bangkok, Thailand. 2 College of Medicine, Rangsit University, Bangkok, Thailand. 3 General Bacteriology Section, National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand. 4 Faculty of Public Health, Kasetsart University Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon, Thailand.
คำสำคัญ (EN): Pertussis; Thailand; Children; Whole-cell pertussis vaccine; Maternal immunization
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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Pertussis surveillance in a children hospital in Bangkok, Thailand
Piyarat Suntarattiwong
1 Queen Sirikit National Institute of Child Health, Bangkok, Thailand. 2 College of Medicine, Rangsit University, Bangkok, Thailand. 3 General Bacteriology Section, National Institute of Health, Department of Medical Sciences, Ministry of Public Health, Nonthaburi, Thailand. 4 Faculty of Public Health, Kasetsart University Chalermphrakiat Sakon Nakhon Province Campus, Sakon Nakhon, Thailand.
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