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Human rotavirus surveillance in hospitalized gastroenteritis cases in Bangkok, Thailand during 2015 - 2018
Ratana Tacharoenmuang - ไม่ระบุหน่วยงาน
ชื่อเรื่อง (EN): Human rotavirus surveillance in hospitalized gastroenteritis cases in Bangkok, Thailand during 2015 - 2018
ผู้แต่ง / หัวหน้าโครงการ (EN): Ratana Tacharoenmuang
บทคัดย่อ (EN): Background: Group A rotaviruses (RVAs) are the leading cause of acute gastroenteritis in infants and young children worldwide. It is also a major cause of death in young children, especially in developing countries in Africa and Asia, and it is estimated that RVA gastroenteritis is associated with 215,000 death in children younger than 5 years old. In Thailand, the RVA detection rate in hospitalized children with gastroenteritis ranges 28.4 to 44.5%. Most of the hospitalized RVA gastroenteritis cases are the young children aged <5 years old. In this study, we surveyed the GP type distribution in the hospitalized gastroenteritis cases in Bangkok, Thailand between January 2015 and December 2018. Materials and Methods: A total of 1,140 stool specimens were collected from hospitalized gastroenteritis cases in Bhumibol Adulyadej hospital, Bangkok, Thailand between January 2015 and December 2018. The specimens were subjected to conventional RT-PCR to assign their GP types. Results: RVA was detected in 429/1,140 (37.6%) stool specimens. The GP types of RVAs belonged to G3P[8] (42.9%), G2P[4] (19.8%), G9P[8] (13.8%), G1P[6] (8.8%), G1P[8] (5.4%), G8P[8] (4.4%), G9P[4] (1.9%), G3P[6] (1.4%), G3P[4] (0.5%), G3P[9] (0.5%), G2P[6] (0.2%), G2P[8] (0.2%) and G8P[4] (0.2%). The average age of RVA gastroenteritis cases was 3Y3M, while the average age of non-RVA gastroenteritis cases was 2Y7M. In this study, the peak of RVA gastroenteritis was found in November 2017 to February 2018. Discussion: The RVA prevalence and GP types were studied in the hospitalized gastroenteritis cases in Thailand between January 2015 and December 2018. G3P[8] was a predominant genotype, but G2P[4], G9P[8], and G1P[6] were detected in a high frequency during the high peak of RVA cases. The precise genome profiles obtained by whole genome nucleotide sequence determination will also be presented.
บทคัดย่อ: ไม่พบข้อมูลจากหน่วยงานต้นทาง
ภาษา (EN): en
เอกสารแนบ (EN): http://nih.dmsc.moph.go.th/research/showimgdetil.php?id=697
เผยแพร่โดย (EN): 1 National Institute of Health, Department of Medical Sciences 2 Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan 3 Bhumibol Adulyadej Hospital, Bangkok 10220, Thailand 4 Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Nonthaburi 11000, Thailand 5 Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
คำสำคัญ (EN): Human
เจ้าของลิขสิทธิ์ (EN): National Institute of Health, Department of Medical Science
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Human rotavirus surveillance in hospitalized gastroenteritis cases in Bangkok, Thailand during 2015 - 2018
Ratana Tacharoenmuang
1 National Institute of Health, Department of Medical Sciences 2 Department of Virology and Parasitology, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan 3 Bhumibol Adulyadej Hospital, Bangkok 10220, Thailand 4 Thailand-Japan Research Collaboration Center on Emerging and Re-emerging Infections, Nonthaburi 11000, Thailand 5 Department of Pediatrics, Fujita Health University School of Medicine, Toyoake, Aichi 470-1192, Japan
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